Background Patients receiving palliative care often have existing comorbidities
necessitating the prescribing of multiple medications. To maximize quality of life in this …

Objective Pharmacy practice has gradually evolved with the paradigm shifted towards
patient-focused practice or medicines optimisation. The advancement of pharmacy-related …

Haloperidol is a poorly water-soluble drug, and its efficacy was limited by dissolution
behavior. This study aimed to improve haloperidol's dissolution rate by nanonization using …

Context Deaths in the intensive care unit (ICU) are increasingly common in the US, yet little
is known about patients' experiences at the end of life in the ICU. Objectives The objective of …

Background Symptomatic control is essential in palliative care, particularly in end-of-life, in
which the pathophysiological changes that characterize this last phase of life strengthen the …

Introduction: A variety of medications are used for symptom control in palliative care, such as
morphine, midazolam and haloperidol. The pharmacokinetics of these drugs may be altered …

Purpose The undesired effects of midazolam can be life-threatening. This paper delineates
the findings related to the pharmacokinetics, adverse effects and drug-drug interactions as …

The transition from active, invasive interventions to comfort care for critical care patients is
often fraught with misunderstandings, conflict and moral distress. The most common issues …

Background and objectives Pain management is a necessary component of palliative care
as most patients suffer from pain during the final phase of life. Due to the complex causation …

Background: Recent and preprohibition studies show that patients with serious illness might
benefit from psychedelic-assisted therapies for a range of symptoms, physical, psychosocial …