PPARγ activators improve glucose homeostasis by stimulating fatty acid uptake in the adipocytes
It is currently thought that the effects of PPARγ activation on glucose homeostasis may be
due to the effect of this nuclear receptor on the production of adipocyte-derived signalling …
due to the effect of this nuclear receptor on the production of adipocyte-derived signalling …
Apolipoprotein C-III and hepatic triglyceride-rich lipoprotein production
Z Yao, Y Wang - Current opinion in lipidology, 2012 - journals.lww.com
The current review summarizes recent experimental evidence for an intrahepatic role of
human apo C-III in promoting mobilization and utilization of triglyceride during VLDL 1 …
human apo C-III in promoting mobilization and utilization of triglyceride during VLDL 1 …
ApoC-III ASO promotes tissue LPL activity in the absence of apoE-mediated TRL clearance
B Ramms, S Patel, C Nora, AR Pessentheiner… - Journal of lipid …, 2019 - ASBMB
Hypertriglyceridemia results from accumulation of triglyceride (TG)-rich lipoproteins (TRLs)
in the circulation and is associated with increased CVD risk. ApoC-III is an apolipoprotein on …
in the circulation and is associated with increased CVD risk. ApoC-III is an apolipoprotein on …
HDL, atherosclerosis, and emerging therapies
A Hafiane, J Genest - Cholesterol, 2013 - Wiley Online Library
This review aims to provide an overview on the properties of high‐density lipoproteins
(HDLs) and their cardioprotective effects. Emergent HDL therapies will be presented in the …
(HDLs) and their cardioprotective effects. Emergent HDL therapies will be presented in the …
Science behind the cardio-metabolic benefits of omega-3 polyunsaturated fatty acids: biochemical effects vs. clinical outcomes
Lower incidence of cardiovascular disease (CVD) in the Greenland Inuit, Northern Canada
and Japan has been attributed to their consumption of seafood rich in long chain omega-3 …
and Japan has been attributed to their consumption of seafood rich in long chain omega-3 …
Historical perspective: phosphatidylserine and phosphatidylethanolamine from the 1800s to the present
JE Vance - Journal of lipid research, 2018 - ASBMB
This article provides a historical account of the discovery, chemistry, and biochemistry of two
ubiquitous phosphoglycerolipids, phosphatidylserine (PS) and phosphatidylethanolamine …
ubiquitous phosphoglycerolipids, phosphatidylserine (PS) and phosphatidylethanolamine …
Modulation of rat liver apolipoprotein gene expression and serum lipid levels by tetradecylthioacetic acid (TTA) via PPARα activation
E Raspé, L Madsen, AM Lefebvre, I Leitersdorf… - Journal of lipid …, 1999 - ASBMB
3-Thia fatty acids are modified fatty acids that promote hepatic peroxisome proliferation and
decrease serum triacylglycerol, cholesterol and free fatty acid levels in rats. In vivo …
decrease serum triacylglycerol, cholesterol and free fatty acid levels in rats. In vivo …
Angptl3-null mice show low plasma lipid concentrations by enhanced lipoprotein lipase activity
K Fujimoto, R Koishi, T Shimizugawa… - Experimental animals, 2006 - jstage.jst.go.jp
Angiopoietin-like 3 (ANGPTL3) is a secreted protein with both angiogenesis and lipid
metabolism functions. We generated knockout mice that failed to express the Angptl3 gene …
metabolism functions. We generated knockout mice that failed to express the Angptl3 gene …
A decreased expression of angiopoietin-like 3 is protective against atherosclerosis in apoE-deficient mice
Y Ando, T Shimizugawa, S Takeshita, M Ono… - Journal of lipid …, 2003 - ASBMB
KK/Snk mice (previously KK/San) possessing a recessive mutation (hypl) of the angiopoietin-
like 3 (Angptl3) gene homozygously exhibit a marked reduction of VLDL due to the …
like 3 (Angptl3) gene homozygously exhibit a marked reduction of VLDL due to the …
Apolipoprotein CIII deficiency protects against atherosclerosis in knockout rabbits
H Yan, M Niimi, F Matsuhisa, H Zhou… - … , and vascular biology, 2020 - Am Heart Assoc
Objective: Apo (apolipoprotein) CIII mediates the metabolism of triglyceride (TG)-rich
lipoproteins. High levels of plasma apoCIII are positively correlated with the plasma TG …
lipoproteins. High levels of plasma apoCIII are positively correlated with the plasma TG …