Vaccines against pertussis have been used for more than a hundred years. This review
describes the development of whole-cell (wP) and acellular pertussis (aP) vaccines, which …

Introduction Whole cell and acellular pertussis vaccines have been very effective in
decreasing the deaths of neonates and infants from Bordetella pertussis. Despite high …

Bordetella pertussis whole-cell vaccines (wP) caused a spectacular drop of global pertussis
incidence, but since the replacement of wP with acellular pertussis vaccines (aP), pertussis …

Abstract Background In Germany, antenatal influenza vaccination is recommended since
2010, but uptake remains low. Several countries recently introduced antenatal pertussis …

Importance An alternative option to maternal vaccination to prevent severe pertussis in
infants is vaccination at birth. Data are needed on the immunogenicity and safety of a birth …

Introduction Recombinant acellular pertussis (ap) vaccines containing genetically
inactivated pertussis toxin (PT gen) and filamentous hemagglutinin (FHA) with or without …

B. pertussis is a human-specific pathogen and the causative agent of whooping cough. The
ongoing resurgence in pertussis incidence in high income countries is likely due to faster …

Pertussis, also known as whooping cough, is caused by the Gram negative bacterium
Bordetella pertussis. 1 It is transmitted via airborne droplets and is highly infectious. 2 …

Background Recombinant pertussis vaccines inducing long-lasting immune responses
could help to control the rise in pertussis. We here report on persisting antibody responses 2 …

Neither immunization nor recovery from natural infection provides life-long protection
against Bordetella pertussis. Replacement of a whole-cell pertussis (wP) vaccine with an …