Oxidative stress and inflammation play an important role in the pathophysiological changes
of liver diseases. Nuclear factor erythroid 2-related factor 2 (NRF2) is a transcription factor …

Objectives It is unclear if a high level of alcohol consumption is a risk factor for liver fibrosis
for people living with HIV (PLWH). This study systematically summarizes the risk relationship …

Mulberrin (Mul) is a key component of the traditional Chinese medicine Romulus Mori with
various biological functions. However, the effects of Mul on liver fibrosis have not been …

Background Liver fibrosis is a crucial progress to deteriorate liver disease. E Se tea (ES) is
an ethnic herbal tea in China that has various biological activities for human beings …

Oxidative stress induced by chemotherapeutic agents causes hepatotoxicity. 5-Fluorouracil
(5-FU) has been found to have a variety of side effects, but its toxic effect on the liver and the …

The liver is an important metabolic organ, and acute liver injury (ALI) is potentially lethal.
Itaconate, a metabolic intermediate from the tricarboxylic acid cycle, showed emerging anti …

Alpinetin is the major active ingredient of Alpiniakatsumadai Hayata. As a kind of novel plant-
derived flavonoid, alpinetin has shown potent hepatoprotective effect against many liver …

Activation of hepatic stellate cells (HSCs) constitutes a crucial etiological factor leading to
liver fibrosis. Theaflavine (TF) is a characteristic bioactive compound in fermented tea. Here …

Cadmium (Cd) is a common environmental pollutant with known toxic effects on the liver.
Puerarin (PU), a natural flavonoid, has been shown to exert protective effect in numerous …

Fibrosis is a persistent inflammatory response that causes scarring and tissue sclerosis by
stimulating myofibroblasts to create significant quantities of extracellular matrix protein …