Recent antitumor drug research has seen the development of a large variety of tyrosine
kinase inhibitors (TKIs) with increasing specificity and selectivity. These are highly promising …

The epidermal growth factor receptor (EGFR) plays a prominent role in cell growth and
development. Its regulation in humans is complex and incompletely understood. In this …

Novel therapeutic agents that target the epidermal growth factor receptor (EGFR) constitute
an important addition to the therapeutic armamentarium for the treatment of metastatic …

Simple Summary Biomarkers for the prediction and efficacy of therapies are an urgent
necessity for lung cancer patients. In this article, we summarize genomic and proteomic …

Protein-tyrosine phosphatases (PTPs) counteract protein tyrosine phosphorylation and
cooperate with receptor-tyrosine kinases in the regulation of cell signaling. PTPs need to …

A novel series of hybrid analogues of monastrol-1, 3, 5-triazine were designed and
developed via one-pot synthesis using Bi (NO3) 3 as a catalyst. Entire compounds were …

BACKGROUND: Epidermal growth factor receptor (EGFR) is coactivated by the μ-opioid
receptor (MOR), expressed on non–small cell lung cancer (NSCLC) cells and human lung …

Trop‐2, a cell surface glycoprotein, contains both extracellular epidermal growth factor‐like
and thyroglobulin type‐1 repeat domains. Low TROP2 expression was observed in lung …

It is well recognized that the presence of cervical lymph node metastasis is the most
important prognostic factor in oral squamous cell carcinoma (OSCC). In solid epithelial …

Aim: This study aimed at developing antibody-functionalized gold nanoparticles (AuNPs) to
selectively target cancer cells and probing their potential radiosensitizing effects under …