There is now overwhelming evidence to support lowering LDL-c (low-density lipoprotein
cholesterol) to reduce cardiovascular morbidity and mortality. Statins are a class of drugs …

Since the publication of the 2012 guidelines new literature has emerged to inform decision-
making. The 2016 guidelines primary panel selected a number of clinically relevant …

Hyperlipidemia is a major risk factor for cardiovascular morbidity and mortality. Statins are
the first-choice therapy for dyslipidemias and are considered the cornerstone of …

Hydroxy-methyl-glutaryl-coenzyme A (HMG-CoA) reductase inhibitors or statins are well
tolerated, but associated with various statin-associated symptoms (SAS), including statin …

Statin-associated muscle symptoms (SAMS) are one of the principal reasons for statin non-
adherence and/or discontinuation, contributing to adverse cardiovascular outcomes. This …

An initiation-promotion protocol was used to test the hypothesis that unleaded gasoline (UG)
vapor acts as a liver tumor promoter in female mice under exposure conditions in which UG …

Aim We tested the hypothesis that statin-related news stories, cardiovascular disease,
diabetes, statin dose, calendar year, and socio-demographic status are associated with …

Abstract The Canadian Consensus Working Group has updated its evaluation of the
literature pertaining to statin intolerance and adverse effects. This overview introduces a …

Statins are one of the most commonly prescribed drugs in clinical practice. They are usually
well tolerated and effectively prevent cardiovascular events. Most adverse effects associated …

Statin therapy is generally well tolerated and very effective in the prevention and treatment of
cardiovascular disease, regardless of cholesterol levels; however, it can be associated with …