Importance Survival from sepsis has improved in recent years, resulting in an increasing
number of patients who have survived sepsis treatment. Current sepsis guidelines do not …

Background Survivors of critical illness often experience poor outcomes after hospitalisation,
including delayed return to work, which carries substantial economic consequences …

Background Early, goal-directed therapy (EGDT) is recommended in international
guidelines for the resuscitation of patients presenting with early septic shock. However …

Objective To identify research priorities in the management, epidemiology, outcome and
underlying causes of sepsis and septic shock. Design A consensus committee of 16 …

Background Emergency medical services (EMS) personnel have already made substantial
contributions to improving care for patients with time-dependent illnesses, such as trauma …

Bloodstream infections are associated with considerable morbidity and health care costs.
Molecular rapid diagnostic tests (mRDTs) are a promising complement to conventional …

Purpose To describe the design and initial implementation of an Intensive Care Unit
Recovery Center (ICU-RC) in the United States. Materials and methods A prospective …

Objective: Frailty is a multidimensional syndrome characterized by loss of physiologic
reserve that gives rise to vulnerability to poor outcomes. We aimed to examine the …

Background The purpose of this study was to examine hospital mortality, long-term mortality,
and health service utilization among critically ill patients. We also determined whether these …

Objectives: This study sought to examine mortality, health-related quality of life, and physical
function among sepsis survivors who developed chronic critical illness. Design: Single …