Cytotoxicity and mechanism of action of metal complexes: An overview
After the discovery of cisplatin, many metal compounds were investigated for the therapy of
diseases, especially cancer. The high therapeutic potential of metal-based compounds is …
diseases, especially cancer. The high therapeutic potential of metal-based compounds is …
Nascent pharmacological advancement in adamantane derivatives
The adamantane moiety has attracted significant attention since its discovery in 1933 due to
its remarkable structural, chemical, and medicinal properties. This molecule has a notable …
its remarkable structural, chemical, and medicinal properties. This molecule has a notable …
[HTML][HTML] Two adamantan-1-amine-based scaffolds: Synthesis, crystallographic synthons, TD/DFT calculations, in-depth molecular docking/ADME/T simulations, and …
This work synthesized and structurally characterized the two adamantan-1-amine-based
compounds, C 10 H 18 N 2 O 3 (1) and C 21 H 23 NO (2), reacting with adamantan-1-amine …
compounds, C 10 H 18 N 2 O 3 (1) and C 21 H 23 NO (2), reacting with adamantan-1-amine …
Green synthesis, X-ray crystal structure, evaluation as in vitro cytotoxic and antibacterial agents of a new Zn (II) complex containing dipicolinic acid
A Aliabadi, M Zangeneh, Z Izadi, M Badzohre… - Journal of Molecular …, 2022 - Elsevier
A zinc (II) complex formulated as (4-apyH) 2 [Zn (pydc)(pydcH)] 2.(pydcH 2) 2. 10H 2 O was
prepared through a one-pot reaction of pyridine-2, 6-dicarboxylic acid, 4-aminopyridine, and …
prepared through a one-pot reaction of pyridine-2, 6-dicarboxylic acid, 4-aminopyridine, and …
Cd (II) coordination polymer of fumaric acid and pyridyl-hydrazide schiff base: Structure, photoconductivity and theoretical interpretation
Abstract A 2-D coordination polymer,{[Cd 4 (ppmh) 4 (fum) 4 (H 2 O) 4]. 3H 2 O} n (CP)(H 2
fum, fumaric acid; ppmh, N-Pyridin-2-yl-N′-pyridin-4-ylmethylene-hydrazine) has been …
fum, fumaric acid; ppmh, N-Pyridin-2-yl-N′-pyridin-4-ylmethylene-hydrazine) has been …
Synthesis of an amantadine-based novel Schiff base and its transition metal complexes as potential ALP, α-amylase, and α-glucosidase inhibitors
A Ajaz, MA Shaheen, M Ahmed, KS Munawar… - RSC …, 2023 - pubs.rsc.org
A Schiff base ligand HL,(E)-2-((adamantan-1-ylimino) methyl)-6-allylphenol, was
synthesized by condensation of amantadine with 3-allyl-2-hydroxybenzaldehyde, followed …
synthesized by condensation of amantadine with 3-allyl-2-hydroxybenzaldehyde, followed …
Copper-Based Complexes with Adamantane Ring-Conjugated bis(3,5-Dimethyl-pyrazol-1-yl)acetate Ligand as Promising Agents for the Treatment of Glioblastoma
MB Morelli, M Caviglia, C Santini… - Journal of Medicinal …, 2024 - ACS Publications
The new ligand L2Ad, obtained by conjugating the bifunctional species bis (3, 5-
dimethylpyrazol-1-yl)-acetate and the drug amantadine, was used as a chelator for the …
dimethylpyrazol-1-yl)-acetate and the drug amantadine, was used as a chelator for the …
Synthesis, anticancer evaluation and docking studies of novel adamantanyl-1, 3, 4-oxadiazol hybrid compounds as Aurora-A kinase inhibitors
AM Jaber, MM Al-Mahadeen, RA Al-Qawasmeh… - Medicinal Chemistry …, 2023 - Springer
Cancer is a devastating disease, but advancements in cancer treatment offer hope for the
future. Aurora kinases are a family of serine/threonine kinases that play critical roles in cell …
future. Aurora kinases are a family of serine/threonine kinases that play critical roles in cell …
[PDF][PDF] Design, synthesis and biological evaluation of novel 2-hydroxy-1 H-indene-1, 3 (2 H)-dione derivatives as FGFR1 inhibitors
MM Al-Mahadeen, AM Jaber, BO Al-Najjar - Pharmacia, 2024 - pharmacia.pensoft.net
Fibroblast growth-factor receptor (FGFR) is a potential target for cancer therapy. We
synthesised a novel series of FGFR1 inhibitors bearing quinoline, quinoxalin and …
synthesised a novel series of FGFR1 inhibitors bearing quinoline, quinoxalin and …
Ispitivanje citotoksičnosti kompleksa paladijuma (II) sa derivatima tiazola kao ligandima na ćelijama tumora prostate in vitro
D Simić - Универзитет у Крагујевцу, 2022 - nardus.mpn.gov.rs
Biološki aktivne supstance koje u svojoj strukturi sadrže metale su budućnost antitumorske
terapije. Kompleksi metala u zavisnosti od svoje strukture i hemijskih osobina pokazuju …
terapije. Kompleksi metala u zavisnosti od svoje strukture i hemijskih osobina pokazuju …