Treatment and biology of pediatric acute lymphoblastic leukemia

M Kato, A Manabe - Pediatrics International, 2018 - Wiley Online Library
Acute lymphoblastic leukemia (ALL) is the most common pediatric malignancy. In the past
ALL was intractable but now the survival probability is as high as 80–90%. Improved …

Philadelphia chromosome–like acute lymphoblastic leukemia

SK Tasian, ML Loh, SP Hunger - Blood, The Journal of the …, 2017 - ashpublications.org
Philadelphia chromosome (Ph)-like acute lymphoblastic leukemia (ALL), also referred to as
BCR-ABL1–like ALL, is a high-risk subset with a gene expression profile that shares …

Genomic and outcome analyses of Ph-like ALL in NCI standard-risk patients: a report from the Children's Oncology Group

KG Roberts, SC Reshmi, RC Harvey… - Blood, The Journal …, 2018 - ashpublications.org
Philadelphia chromosome–like acute lymphoblastic leukemia (Ph-like ALL; BCR-ABL1–like
ALL) in children with National Cancer Institute (NCI) intermediate-or high-risk (HR) ALL is …

Clinical diagnostics and treatment strategies for Philadelphia chromosome–like acute lymphoblastic leukemia

RC Harvey, SK Tasian - Blood advances, 2020 - ashpublications.org
Philadelphia chromosome-like B-cell acute lymphoblastic leukemia (Ph-like ALL) accounts
for 15% to 30% of B-cell acute lymphoblastic leukemia in older children, adolescents, and …

[HTML][HTML] Advances in B-cell precursor acute lymphoblastic leukemia genomics

C Schwab, CJ Harrison - HemaSphere, 2018 - journals.lww.com
In childhood B-cell precursor acute lymphoblastic leukemia (BCP-ALL), cytogenetic
abnormalities remain important diagnostic and prognostic tools. A number of well …

Outcomes of paediatric patients with B-cell acute lymphocytic leukaemia with ABL-class fusion in the pre-tyrosine-kinase inhibitor era: a multicentre, retrospective …

ML den Boer, G Cario, AV Moorman, JM Boer… - The Lancet …, 2021 - thelancet.com
Background ABL-class fusion genes other than BCR–ABL1 have been identified in
approximately 3% of children with newly diagnosed acute lymphocytic leukaemia, and …

[HTML][HTML] Tyrosine kinase fusion genes in pediatric BCR-ABL1-like acute lymphoblastic leukemia

JM Boer, EMP Steeghs, JRM Marchante, A Boeree… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Approximately 15% of pediatric B cell precursor acute lymphoblastic leukemia (BCP-ALL) is
characterized by gene expression similar to that of BCR-ABL1-positive disease and …

BCR/ABL1–like acute lymphoblastic leukemia: How to diagnose and treat?

S Chiaretti, M Messina, R Foà - Cancer, 2019 - Wiley Online Library
BCR/ABL1–like acute lymphoblastic leukemia (ALL) accounts for 15% to 30% of B‐lineage
ALL, with a peak of incidence occurring in adolescence. This subgroup of patients is …

[HTML][HTML] BCR-ABL1-like acute lymphoblastic leukaemia: From bench to bedside

JM Boer, ML den Boer - European Journal of Cancer, 2017 - Elsevier
Acute lymphoblastic leukaemia (ALL) occurs in approximately 1: 1500 children and is less
frequently found in adults. The most common immunophenotype of ALL is the B cell lineage …

The current genomic and molecular landscape of Philadelphia-like acute lymphoblastic leukemia

P Shiraz, KJ Payne, L Muffly - International Journal of Molecular Sciences, 2020 - mdpi.com
Philadelphia (Ph)-like acute lymphoblastic leukemia (ALL) is a high-risk B-cell Acute
Lymphoblastic Leukemia (B-ALL) characterized by a gene expression profile similar to Ph …