Pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is associated with a high
frequency of copy number alterations (CNAs) in IKZF1, EBF1, PAX5, CDKN2A/B, RB1 …

Philadelphia (Ph)-like acute lymphoblastic leukemia (ALL) is a high-risk B-cell Acute
Lymphoblastic Leukemia (B-ALL) characterized by a gene expression profile similar to Ph …

Philadelphia chromosome-like acute lymphoblastic leukemia (Ph-like ALL) is a recently
described subtype of B-cell precursor ALL with a gene expression profile similar to Ph …

Acute lymphoblastic leukemia (ALL) is a constellation of diseases driven by genetic
alterations commonly derived from structural chromosome rearrangements, aneuploidy and …

The survival rate of children with acute lymphoblastic leukemia (ALL) has increased to
approximately 90% after substantial progress in risk-oriented treatment strategies. Between …

Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer and also occurs in
adults. Although the outcomes of multi-agent chemotherapy regimens have greatly …

Background Structural chromosomal rearrangements that lead to expressed fusion genes
are a hallmark of acute lymphoblastic leukemia (ALL). In this study, we performed …

Philadelphia chromosome-like acute lymphoblastic leukemia (Ph-like ALL), or BCR-ABL1-
like ALL, is a high-risk subtype of B-cell precursor ALL characterized by a gene expression …

Philadelphia-like acute lymphoblastic leukemia (Ph-like ALL) is a high-risk molecular
subtype with a gene expression profile similar to Philadelphia-positive ALL, but not …

JAK2 abnormalities may serve as target for precision medicines in pediatric B-cell precursor
acute lymphoblastic leukemia (BCP-ALL). In the current study we performed a screening for …