Hydroxycamptothecin (HCPT) is a natural plant alkaloid from Camptotheca that shows
potent antitumor activity by targeting intracellular topoisomerase I. However, factors such as …

As the most common form of dementia in humans, Alzheimer's disease (AD) is linked to
misfolding and aggregation of amyloid-β (Aβ) peptides. Gold nanoparticles (AuNPs) can …

Aim: To develop synergistic chemo-photothermal and ferroptosis therapy nanoparticles to
improve the efficacy of treatment for esophageal cancer. Materials & methods: Fe3O4@ PDA …

Breast cancer, as the common malignant carcinoma in women, seriously reduces the life
quality and increases mortality of female worldwide. Fortunately, insufficient chemotherapy …

Due to the difference of the intracellular microenvironment between tumor and normal cells,
many stimuli-responsive drug carriers have been developed for precise drug delivery and …

Cancer remains a major worldwide health challenge. Current studies emphasize the tumor
microenvironment that plays a vital role in tumor proliferation, invasion, metastasis, and drug …

Multidrug resistance (MDR) is one of the leading causes of the failure of cancer
chemotherapy and mainly attributed to the overexpression of drug efflux transporters in …

Biocompatible and biodegradable amphiphilic polymeric micelles (PLA-CMCS-g-OA) were
prepared by surface grafting of oleic acid and polylactic acid onto carboxymethyl chitosan …

Introduction Cancerous tumors are still a major disease that threatens human life, with tumor
multidrug resistance (MDR) being one of the main reasons for the failure of chemotherapy …

Objective Polymer micelles were prepared (L-RSPMs) with luteolin and synthetic RA-SS-
mPEG polymeric material before evaluation of their anti-inflammatory effect on 2, 4, 6-trinitro …