[HTML][HTML] The Role of human epididymis protein 4 in the diagnosis and prognosis of diseases: an umbrella review of systematic reviews and meta-analyses of …

ML Sun, ZY Yang, QJ Wu, YZ Li, XY Li, FH Liu… - Frontiers in …, 2022 - frontiersin.org
Background The application of human epididymis protein 4 (HE4) in diverse health
diseases, especially in cancers, has been extensively studied in recent decades. To …

Kinetics of HE4 and CA125 as prognosis biomarkers during neoadjuvant chemotherapy in advanced epithelial ovarian cancer

JA Alegría-Baños, JC Jiménez-López… - Journal of Ovarian …, 2021 - Springer
Background Ovarian cancer (OC) is considered the most lethal gynecological cancer, of
which more than 65% cases are diagnosed in advanced stages, requiring platinum-based …

[HTML][HTML] Evaluation of HE4 as a prognostic biomarker in uterine cervical cancer

H Dubey, A Ranjan, J Durai, MA Khan… - Cancer Treatment and …, 2023 - Elsevier
Introduction Uterine cervical cancer (UCC) is the fourth most common health problem
worldwide among women. Currently available biomarkers CA125, CA199, and CEA for …

Value of human epididymis secretory protein 4 in differentiating malignant from benign pleural effusion: an analysis of two cohorts

Q Yang, Y Niu, JX Wen, DN Yang… - Therapeutic …, 2023 - journals.sagepub.com
Background: Lung cancer is the most common cause of malignant pleural effusion (MPE).
Serum human epididymis secretory protein 4 (HE4) is a useful diagnostic marker for lung …

[HTML][HTML] Detection and independent validation of model-based quantitative transcriptional regulation relationships altered in lung cancers

M Duan, H Song, C Wang, J Zheng, H Xie… - … in Bioengineering and …, 2020 - frontiersin.org
Differential expressions of genes are widely evaluated for the diagnosis and prognosis
correlations with diseases. But limited studies investigate how transcriptional regulations are …

Human epididymis protein 4, a novel potential biomarker for diagnostic and prognosis monitoring of lung cancer

T Zhang, L Chu, W Tan, C Ye… - The Clinical Respiratory …, 2024 - Wiley Online Library
Objective This study aimed to explore the application value of human epididymis protein 4
(HE4) in diagnosing and monitoring the prognosis of lung cancer. Methods First, TCGA (The …

Development of exploratory algorithms to aid in risk of malignancy prediction of indeterminate pulmonary nodules

N Jeanblanc, L Jackson, S Gawel, S Brophy… - Clinica Chimica …, 2022 - Elsevier
Early detection of lung cancer allows for earlier stage treatment initiation and improved
patient prognosis. This report focuses on utilization of combining patient demographic …

肺癌筛查与早期诊断: 从影像学到生物标志物的进展

何爽, 田金, 龙麟, 赵丽丽, 肖军 - 中国癌症防治杂志, 2024 - zgazfz.com
降低肺癌死亡率最有效的方法是早诊断, 早治疗, 但目前尚未有理想的肺癌筛查和早诊模式.
近年来, 为了提高肺癌的早期诊断率, 降低肺癌患者死亡率, 延长生存期, 越来越多的研究探索 …

Combined use of CYFRA 21-1 and CA 125 predicts survival of patients with metastatic NSCLC and stable disease in IMpower150

A Mang, W Zou, V Rolny, M Reck, D Cigoianu… - Tumor …, 2023 - content.iospress.com
BACKGROUND: Patients with non-small cell lung cancer (NSCLC) and stable disease (SD)
have an unmet clinical need to help guide early treatment adjustments. OBJECTIVE: To …

[PDF][PDF] 血清ProGRP, SCCAg 及HE4 与非小细胞肺癌患者病理特征的关系及其诊断价值分析

王欣欣, 黄松洁, 于洋, 周琳艳… - Progress in Modern …, 2020 - biomed.cnjournals.com
摘要目的: 探讨血清胃泌素释放肽前体(ProGRP), 鳞状上皮细胞癌抗原(SCCAg), 人附睾蛋白4
(HE4) 水平与非小细胞肺癌(NSCLC) 患者病理特征的关系, 分析其对NSCLC 的临床诊断价值 …