1, 2, 3-Triazole-containing hybrids as potential anticancer agents: Current developments, action mechanisms and structure-activity relationships

Z Xu, SJ Zhao, Y Liu - European journal of medicinal chemistry, 2019 - Elsevier
Anticancer agents are critical for the cancer treatment, but side effects and the drug
resistance associated with the currently used anticancer agents create an urgent need to …

An insight on medicinal attributes of 1, 2, 4-triazoles

R Aggarwal, G Sumran - European journal of medicinal chemistry, 2020 - Elsevier
The present review aims to summarize the pharmacological profile of 1, 2, 4-triazole, one of
the emerging privileged scaffold, as antifungal, antibacterial, anticancer, anticonvulsant …

Exploration of 1, 2, 3-triazole linked benzenesulfonamide derivatives as isoform selective inhibitors of human carbonic anhydrase

C Kakakhan, C Türkeş, Ö Güleç, Y Demir… - Bioorganic & Medicinal …, 2023 - Elsevier
Abstract A novel series of 1, 2, 3-triazole benzenesulfonamide substituted 1, 3-
dioxoisoindolin-5-carboxylate (7a-l) inhibitors of human α-carbonic anhydrase (hCA) was …

Recent advances in 1, 2, 3-and 1, 2, 4-triazole hybrids as antimicrobials and their SAR: A critical review

G Tian, Q Song, Z Liu, J Guo, S Cao, S Long - European Journal of …, 2023 - Elsevier
With the widespread use and sometimes even abuse of antibiotics, the problem of bacterial
resistance to antibiotics has become very serious, and it is posing a great threat to global …

Novel 1, 2, 4‐Triazoles as Antifungal Agents

Z Kazeminejad, M Marzi, A Shiroudi… - BioMed Research …, 2022 - Wiley Online Library
The development of innovative antifungal agents is essential. Some fungicidal agents are no
longer effective due to resistance development, various side effects, and high toxicity …

1, 2, 3-Triazole-containing compounds as anti–lung cancer agents: Current developments, mechanisms of action, and structure–activity relationship

T Liang, X Sun, W Li, G Hou, F Gao - Frontiers in pharmacology, 2021 - frontiersin.org
Lung cancer is the most common malignancy and leads to around one-quarter of all cancer
deaths. Great advances have been achieved in the treatment of lung cancer with novel …

Triazole analogues as potential pharmacological agents: A brief review

S Kumar, SL Khokra, A Yadav - Future Journal of Pharmaceutical …, 2021 - Springer
Background A large number of studies have recently reported that, because of their
significant biological and pharmacological properties, heterocyclic compounds and their …

Triazole hybrid compounds: A new frontier in malaria treatment

L Ravindar, SA Hasbullah, KP Rakesh… - European Journal of …, 2023 - Elsevier
Reviewing the advancements in malaria treatment, the emergence of triazole hybrid
compounds stands out as a groundbreaking development. Combining the advantages of …

1, 2, 3-Triazole-containing hybrids with potential antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA)

Z Xu - European journal of medicinal chemistry, 2020 - Elsevier
Methicillin-resistant Staphylococcus aureus (MRSA), as a classic reason for genuine skin
and flimsy tissues diseases, is a worldwide general wellbeing risk and has already …

Recent accomplishments on the synthetic/biological facets of pharmacologically active 1H-1, 2, 3-triazoles

S Kumar, B Sharma, V Mehra, V Kumar - European Journal of Medicinal …, 2021 - Elsevier
The continuous demand of medicinally important scaffolds has prompted the synthetic
chemists to identify simple and efficient routes for their synthesis. 1H-1, 2, 3-triazole …