Purpose: Early detection of pancreatic ductal adenocarcinoma (PDAC) remains elusive.
Precursor lesions of PDAC, specifically intraductal papillary mucinous neoplasms (IPMNs) …

Br east Ca ncer 1 (BRCA1) gene is a well-characterized tumor suppressor gene, mutations
of which are primarily found in women with breast and ovarian cancers. B RCA1-a ssociated …

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive, highly metastatic malignancy
and accounts for 85% of pancreatic cancers. PDAC patients have poor prognosis with a five …

Background Immunoglobulin-related genes are associated with the favorable prognosis of
triple-negative breast cancer (TNBC) patients. We aimed to analyze the function and …

Mutations at the TP53 gene are readily detected (approximately 50–75%) in pancreatic
ductal adenocarcinoma (PDAC) patients. TP53 was previously thought to be a difficult target …

In this brief survey, various aspects of cancer complexity and how this complexity can be
confronted using modern complex networks' theory and gene expression datasets, are …

Exploring the underlying mechanisms of cancer development is useful for cancer treatment.
In this paper, we analyzed the transcriptome profiles from the human normal pancreas …

For studying the pathogenesis of complex diseases, it is important to identify the disease
modules in the system level. Since the protein-protein interaction (PPI) networks contain a …

摘要S100A14 是多功能S100 蛋白家族的成员之一, 具有广泛的生物学功能, 如细胞增殖,
分化与凋亡, 侵袭与转移等. 它在多种肿瘤中的表达具有细胞和组织特异性, 而且表达水平与患者 …

We propose a two‐way additive model with group‐specific interactions, where the group
information is unknown. We treat the group membership as latent information and propose …