SNPs in miRNAs and target sequences: role in cancer and diabetes

Y Chhichholiya, AK Suryan, P Suman, A Munshi… - Frontiers in …, 2021 - frontiersin.org
miRNAs are fascinating molecular players for gene regulation as individual miRNA can
control multiple targets and a single target can be regulated by multiple miRNAs. Loss of …

[HTML][HTML] MicroRNA and diabetic retinopathy—biomarkers and novel therapeutics

Z Smit-McBride, LS Morse - Annals of translational medicine, 2021 - ncbi.nlm.nih.gov
Diabetic retinopathy (DR) accounts for~ 80% of legal blindness in persons aged 20–74
years and is associated with enormous social and health burdens. Current therapies are …

Expression of miR-1-3p, miR-16-5p and miR-122-5p as possible risk factors of secondary cardiovascular events

R Badacz, P Kleczyński, J Legutko, K Żmudka, J Gacoń… - Biomedicines, 2021 - mdpi.com
Ischemic event in one arterial territory increases the risk of a subsequent ischemic event.
Circulating microRNAs (miRs) emerge as a potential clinical tool to assess risk of …

MDMF: predicting miRNA–disease association based on matrix factorization with disease similarity constraint

J Ha - Journal of Personalized Medicine, 2022 - mdpi.com
MicroRNAs (miRNAs) have drawn enormous attention owing to their significant roles in
various biological processes, as well as in the pathogenesis of human diseases. Therefore …

Roles of extracellular vesicles associated non-coding RNAs in Diabetes Mellitus

BR Gauthier, N Cobo-Vuilleumier… - Frontiers in …, 2022 - frontiersin.org
Extracellular vesicles (EVs), especially exosomes (50 to 150 nm), have been shown to play
important roles in a wide range of physiological and pathological processes, including …

Role of selected miRNAs as diagnostic and prognostic biomarkers in cardiovascular diseases, including coronary artery disease, myocardial infarction and …

R Mir, I Elfaki, N Khullar, AA Waza, C Jha… - Journal of …, 2021 - mdpi.com
Cardiovascular diseases are the leading cause of death worldwide in different cohorts. It is
well known that miRNAs have a crucial role in regulating the development of cardiovascular …

rs41291957 controls miR‐143 and miR‐145 expression and impacts coronary artery disease risk

IF Hall, M Climent, C Viviani Anselmi… - EMBO Molecular …, 2021 - embopress.org
The role of single nucleotide polymorphisms (SNPs) in the etiopathogenesis of
cardiovascular diseases is well known. The effect of SNPs on disease predisposition has …

Association of miRNA-499 rs3746444 A> G genotype variants with type 2 diabetes mellitus and its coronary heart disease complication in adult Egyptian population

HES Oraby, SS Elshaer, LA Rashed, NAR Eldesoky - Gene Reports, 2022 - Elsevier
Background Type 2 diabetes mellitus (T2DM) is a worldwide health problem. Prolonged
elevated glucose level might cause serious cardiovascular complications. MicroRNA-499 …

Non-coding RNAs and exosomal non-coding RNAs in diabetic retinopathy: a narrative review

Y Zhong, J Xia, L Liao, MR Momeni - International Journal of Biological …, 2023 - Elsevier
Diabetic retinopathy (DR) is a devastating complication of diabetes, having extensive and
resilient effects on those who suffer from it. As yet, the underlying cell mechanisms of this …

[HTML][HTML] Genetic test for the personalization of sport training

Z Naureen, M Perrone, S Paolacci… - Acta Bio Medica …, 2020 - ncbi.nlm.nih.gov
Genetic variants may contribute to confer elite athlete status. However, this does not mean
that a person with favourable genetic traits would become a champion because multiple …