Loop-mediated isothermal amplification (LAMP): a rapid, accurate, and cost-effective diagnostic method for infectious diseases

Y Mori, T Notomi - Journal of infection and chemotherapy, 2009 - Elsevier
Loop-mediated isothermal amplification (LAMP) is an established nucleic acid amplification
method offering rapid, accurate, and cost-effective diagnosis of infectious diseases. This …

Antimalarial drug discovery: efficacy models for compound screening

DA Fidock, PJ Rosenthal, SL Croft, R Brun… - Nature reviews Drug …, 2004 - nature.com
Increased efforts in antimalarial drug discovery are urgently needed. The goal must be to
develop safe and affordable new drugs to counter the spread of malaria parasites that are …

Simple and inexpensive fluorescence-based technique for high-throughput antimalarial drug screening

M Smilkstein, N Sriwilaijaroen, JX Kelly… - Antimicrobial agents …, 2004 - Am Soc Microbiol
Radioisotopic assays involve expense, multistep protocols, equipment, and radioactivity
safety requirements which are problematic in high-throughput drug testing. This study …

The global distribution and population at risk of malaria: past, present, and future

SI Hay, CA Guerra, AJ Tatem, AM Noor… - The Lancet infectious …, 2004 - thelancet.com
The aim of this review was to use geographic information systems in combination with
historical maps to quantify the anthropogenic impact on the distribution of malaria in the 20th …

Sensitive and Inexpensive Molecular Test for Falciparum Malaria: Detecting Plasmodium falciparum DNA Directly from Heat-Treated Blood by Loop-Mediated …

LLM Poon, BWY Wong, EHT Ma, KH Chan… - Clinical …, 2006 - academic.oup.com
Background: Malaria is one of the most important parasitic infections in humans. A sensitive
diagnostic test for malaria that could be applied at the community level could be useful in …

[HTML][HTML] Standardizing the measurement of parasite clearance in falciparum malaria: the parasite clearance estimator

JA Flegg, PJ Guerin, NJ White, K Stepniewska - Malaria journal, 2011 - Springer
Background A significant reduction in parasite clearance rates following artesunate
treatment of falciparum malaria, and increased failure rates following artemisinin …

Effectiveness of antimalarial drugs

JK Baird - New England Journal of Medicine, 2005 - Mass Medical Soc
A global resurgence of malaria has taken place as a result of a lapse in preventive efforts
and the emergence of resistance to standard antimalarial drugs. New therapies are …

Malaria management: past, present, and future

A Enayati, J Hemingway - Annual review of entomology, 2010 - annualreviews.org
The prospect of malaria eradication has been raised recently by the Bill and Melinda Gates
Foundation with support from the international community. There are significant lessons to …

Schistosomiasis and soil-transmitted helminthiasis: common drugs for treatment and control

J Utzinger, J Keiser - Expert opinion on pharmacotherapy, 2004 - Taylor & Francis
Schistosomiasis is a disease caused by parasitic trematode worms (schistosomes) that
currently affects 200 million people living in tropical and subtropical environments. It is a …

[HTML][HTML] Drug uptake and modulation of drug resistance in Leishmania by an aquaglyceroporin

B Gourbal, N Sonuc, H Bhattacharjee, D Legare… - Journal of Biological …, 2004 - ASBMB
Leishmaniasis is a protozoan parasitic disease that affects 12 million people worldwide. The
first line choice for the treatment of this disease is antimonial drugs. In the endemic regions …