Ophidian envenomation strategies and the role of purines
SD Aird - Toxicon, 2002 - Elsevier
Snake envenomation employs three well integrated strategies: prey immobilization via
hypotension, prey immobilization via paralysis, and prey digestion. Purines (adenosine …
hypotension, prey immobilization via paralysis, and prey digestion. Purines (adenosine …
Local renin–angiotensin systems: the unanswered questions
AHJ Danser - The international journal of biochemistry & cell biology, 2003 - Elsevier
The concept of local renin–angiotensin systems has been introduced almost 20 years ago to
explain the beneficial blood pressure-independent effects of ACE inhibitors and AT1 …
explain the beneficial blood pressure-independent effects of ACE inhibitors and AT1 …
Angiotensin II disrupts inhibitory avoidance memory retrieval
The brain renin–angiotensin system (RAS) is involved in learning and memory, but the
actual role of angiotensin II (AII) and its metabolites in this process has been difficult to …
actual role of angiotensin II (AII) and its metabolites in this process has been difficult to …
Angiotensin II blocks memory consolidation through an AT2 receptor-dependent mechanism
Rationale and objectives Several studies suggest that the brain renin–angiotensin system is
involved in memory consolidation. However, the participation of angiotensin II (AII) in this …
involved in memory consolidation. However, the participation of angiotensin II (AII) in this …
Chronic perfusion of angiotensin II causes cognitive dysfunctions and anxiety in mice
S Duchemin, E Belanger, R Wu, G Ferland… - Physiology & …, 2013 - Elsevier
High blood pressure is a major risk factor in the onset of cerebrovascular diseases and
cognitive impairment. However, mechanisms by which these occur remain unclear and …
cognitive impairment. However, mechanisms by which these occur remain unclear and …
Novel angiotensin II AT1 receptor antagonist irbesartan prevents thromboxane A2-induced vasoconstriction in canine coronary arteries and human platelet …
P Li, M Fukuhara, DI Diz, CM Ferrario… - Journal of Pharmacology …, 2000 - ASPET
This study was conducted to investigate whether the novel orally active nonpeptide
angiotensin II (Ang II) AT1 receptor antagonist irbesartan interacts with the thromboxane …
angiotensin II (Ang II) AT1 receptor antagonist irbesartan interacts with the thromboxane …
Novel AT1 Receptor–Independent Functions of Losartan
J Sadoshima - Circulation research, 2002 - Am Heart Assoc
Although currently available angiotensin II type 1 (AT1) receptor blockers (ARBs) share a
common mechanism of action, blocking AT1 receptors, their receptor binding kinetics and …
common mechanism of action, blocking AT1 receptors, their receptor binding kinetics and …
Nonpeptide angiotensin II antagonist losartan inhibits thromboxane A2-induced contractions in canine coronary arteries
P Li, CM Ferrario, KB Brosnihan - Journal of Pharmacology and …, 1997 - ASPET
We investigated the selectivity of a nonpeptide angiotensin II AT1 receptor antagonist
losartan for the vascular thromboxane A2 (TxA2)/prostaglandin endoperoxide (PGH2) …
losartan for the vascular thromboxane A2 (TxA2)/prostaglandin endoperoxide (PGH2) …
Molecular-specific effects of angiotensin II antagonists: clinical relevance to treating hypertension?
JL Reid - Journal of the Renin-Angiotensin-Aldosterone …, 2005 - journals.sagepub.com
Angiotensin II receptor blockers (ARBs) may produce a number of molecule-specific effects
that appear to be independent of interaction with the angiotensin II type 1 (AT 1)-receptor …
that appear to be independent of interaction with the angiotensin II type 1 (AT 1)-receptor …
Losartan influences behavioural effects of angiotensin II (3–7) in rats
W Karwowska-Polecka, A Kułakowska… - Pharmacological …, 1997 - Elsevier
We have previously shown that angiotensin II (3–7)[Ang II (3–7)] stimulates behavioural
activity of rats similar to angiotensin II (Ang II). The involvement of AT1angiotensin receptors …
activity of rats similar to angiotensin II (Ang II). The involvement of AT1angiotensin receptors …