Snake envenomation employs three well integrated strategies: prey immobilization via
hypotension, prey immobilization via paralysis, and prey digestion. Purines (adenosine …

The concept of local renin–angiotensin systems has been introduced almost 20 years ago to
explain the beneficial blood pressure-independent effects of ACE inhibitors and AT1 …

The brain renin–angiotensin system (RAS) is involved in learning and memory, but the
actual role of angiotensin II (AII) and its metabolites in this process has been difficult to …

Rationale and objectives Several studies suggest that the brain renin–angiotensin system is
involved in memory consolidation. However, the participation of angiotensin II (AII) in this …

High blood pressure is a major risk factor in the onset of cerebrovascular diseases and
cognitive impairment. However, mechanisms by which these occur remain unclear and …

This study was conducted to investigate whether the novel orally active nonpeptide
angiotensin II (Ang II) AT1 receptor antagonist irbesartan interacts with the thromboxane …

Although currently available angiotensin II type 1 (AT1) receptor blockers (ARBs) share a
common mechanism of action, blocking AT1 receptors, their receptor binding kinetics and …

We investigated the selectivity of a nonpeptide angiotensin II AT1 receptor antagonist
losartan for the vascular thromboxane A2 (TxA2)/prostaglandin endoperoxide (PGH2) …

Angiotensin II receptor blockers (ARBs) may produce a number of molecule-specific effects
that appear to be independent of interaction with the angiotensin II type 1 (AT 1)-receptor …

We have previously shown that angiotensin II (3–7)[Ang II (3–7)] stimulates behavioural
activity of rats similar to angiotensin II (Ang II). The involvement of AT1angiotensin receptors …