In health, indigenous polymicrobial communities at mucosal surfaces maintain an ecological
balance via both inter‐microbial and host‐microbial interactions that promote their own and …

Macrophages are key cellular components of the innate immunity, acting as the main player
in the first‐line defence against the pathogens and modulating homeostatic and …

Periodontitis is a dysbiotic inflammatory disease with an adverse impact on systemic health.
Recent studies have provided insights into the emergence and persistence of dysbiotic oral …

The pathogenesis of periodontitis involves a complex immune/inflammatory cascade that is
initiated by the bacteria of the oral biofilm that forms naturally on the teeth. The susceptibility …

Oral squamous cell carcinoma (OSCC) is a lethal disease whose incidence is increasing.
Epidemiologic studies demonstrate an association between periodontitis and oral cancer …

Periodontitis, or gum disease, affects millions of people each year. Although it is associated
with a defined microbial composition found on the surface of the tooth and tooth root, the …

In their classic 1976 paper, Page & Schroeder described the histopathologic events and the
types of myeloid cells and lymphocytes involved in the initiation and progression of …

Recent metagenomic and mechanistic studies are consistent with a new model of
periodontal pathogenesis. This model proposes that periodontal disease is initiated by a …

Neutrophils have been historically associated with antimicrobial functions in acute infections
but are now appreciated as functionally versatile cells with critical roles in chronic …

The article discusses the protective and destructive roles of cytokine responses against
periodontal infections. It stresses the activities and functions of the protein molecule …