Periodontopathic bacteria constantly stimulate the host, which causes an immune response,
leading to host‐induced periodontal tissue damage. The complex interaction and imbalance …

We report a mechanism of microbial evasion of Toll-like receptor (TLR)-mediated immunity
that depends on CXCR4 exploitation. Specifically, the oral/systemic pathogen …

Porphyromonas gingivalis is a primary etiological agent of chronic periodontal disease, an
infection-driven chronic inflammatory disease that leads to the resorption of tooth-supporting …

Porphyromonas gingivalis is an oral/systemic pathogen implicated in chronic conditions,
although the mechanism (s) whereby it resists immune defenses and persists in the host is …

Periodontitis is an inflammatory disease characterized by periodontal pocket formation and
alveolar bone resorption. Periodontal bone resorption is induced by osteoclasts and …

M-CSF and RANKL are two crucial cytokines stimulating differentiation of mature, bone
resorbing, multinucleated osteoclasts from mononucleated progenitor cells in the monocyte …

Rheumatoid arthritis (RA) is a systemic immune mediated inflammatory disease of unknown
origin, which is predominantly affecting the joints. Antibodies against citrullinated peptides …

When excessively activated or deregulated, complement becomes a major link between
infection and inflammatory pathology including periodontitis. This oral inflammatory disease …

Porphyromonas gingivalis is strongly correlated with chronic periodontitis. Its chronic
persistence in the periodontium depends on its ability to evade host immunity without …

Background: Maternal periodontal disease is found in≤ 40% of pregnant women and is
associated with adverse pregnancy outcomes. Vitamin D deficiency may play a role in …