Distinct lipid a moieties contribute to pathogen-induced site-specific vascular inflammation
C Slocum, SR Coats, N Hua, C Kramer… - PLoS …, 2014 - journals.plos.org
Several successful pathogens have evolved mechanisms to evade host defense, resulting in
the establishment of persistent and chronic infections. One such pathogen, Porphyromonas …
the establishment of persistent and chronic infections. One such pathogen, Porphyromonas …
Direct Recognition of Fusobacterium nucleatum by the NK Cell Natural Cytotoxicity Receptor NKp46 Aggravates Periodontal Disease
S Chaushu, A Wilensky, C Gur, L Shapira… - PLoS …, 2012 - journals.plos.org
Periodontitis is a common human chronic inflammatory disease that results in the
destruction of the tooth attachment apparatus and tooth loss. Although infections with …
destruction of the tooth attachment apparatus and tooth loss. Although infections with …
Polymeric carriers for delivery systems in the treatment of chronic periodontal disease
Periodontitis (PD) is a chronic inflammatory disease of periodontal tissues caused by
pathogenic microorganisms and characterized by disruption of the tooth-supporting …
pathogenic microorganisms and characterized by disruption of the tooth-supporting …
[HTML][HTML] Porphyromonas gingivalis Stimulates TLR2-PI3K Signaling to Escape Immune Clearance and Induce Bone Resorption Independently of MyD88
H Makkawi, S Hoch, E Burns, K Hosur… - Frontiers in cellular …, 2017 - frontiersin.org
Porphyromonas gingivalis is a gram-negative anaerobic periodontal pathogen that persists
in dysbiotic mixed-species biofilms alongside a dense inflammatory infiltrate of neutrophils …
in dysbiotic mixed-species biofilms alongside a dense inflammatory infiltrate of neutrophils …
Role of infections in the pathogenesis of rheumatoid arthritis: Focus on mycobacteria
Rheumatoid arthritis (RA) is a systemic inflammatory autoimmune disease characterized by
chronic erosive polyarthritis. A complex interaction between a favorable genetic background …
chronic erosive polyarthritis. A complex interaction between a favorable genetic background …
Periodontitis‐associated pathogens P. gingivalis and A. actinomycetemcomitans activate human CD14+ monocytes leading to enhanced Th17/IL‐17 responses
WC Cheng, SD van Asten, LA Burns… - European journal of …, 2016 - Wiley Online Library
The Th17/IL‐17 pathway is implicated in the pathogenesis of periodontitis (PD), however the
mechanisms are not fully understood. We investigated the mechanism by which the …
mechanisms are not fully understood. We investigated the mechanism by which the …
[HTML][HTML] Complement-dependent mechanisms and interventions in periodontal disease
G Hajishengallis, T Kajikawa, E Hajishengallis… - Frontiers in …, 2019 - frontiersin.org
Periodontitis is a prevalent inflammatory disease that leads to the destruction of the tooth-
supporting tissues. Current therapies are not effective for all patients and this oral disease …
supporting tissues. Current therapies are not effective for all patients and this oral disease …
[HTML][HTML] The role of skin and orogenital microbiota in protective immunity and chronic immune-mediated inflammatory disease
YJ Park, HK Lee - Frontiers in immunology, 2018 - frontiersin.org
The skin and orogenital mucosae, which constitute complex protective barriers against
infection and injuries, are not only the first to come into contact with pathogens but are also …
infection and injuries, are not only the first to come into contact with pathogens but are also …
[HTML][HTML] Interactions between neutrophils and periodontal pathogens in late-onset periodontitis
Late-onset periodontitis is associated with a series of inflammatory reactions induced by
periodontal pathogens, such as Porphyromonas gingivalis, a keystone pathogen involved in …
periodontal pathogens, such as Porphyromonas gingivalis, a keystone pathogen involved in …
TLR2 promoter hypermethylation creates innate immune dysbiosis
M Benakanakere, M Abdolhosseini… - Journal of dental …, 2015 - journals.sagepub.com
Periodontitis is a common chronic inflammatory disease that is initiated by a complex
microbial biofilm that poses significant health and financial burdens globally …
microbial biofilm that poses significant health and financial burdens globally …