Antioxidant and anti-inflammatory effect of Nrf2 inducer dimethyl fumarate in neurodegenerative diseases

SA Scuderi, A Ardizzone, I Paterniti, E Esposito… - Antioxidants, 2020 - mdpi.com
Neurodegenerative diseases (NDs) represents debilitating conditions characterized by
degeneration of neuronal cells in specific brain areas, causing disability and death in …

[HTML][HTML] GSK-3β: An exuberating neuroinflammatory mediator in Parkinson's disease

SS Khan, S Janrao, S Srivastava, SB Singh… - Biochemical …, 2023 - Elsevier
Neuroinflammation is a critical degradative condition affecting neurons in the brain.
Progressive neurodegenerative conditions such as Alzheimer's disease and Parkinson's …

Informing deep neural networks by multiscale principles of neuromodulatory systems

J Mei, E Muller, S Ramaswamy - Trends in Neurosciences, 2022 - cell.com
Our brains have evolved the ability to configure and adapt their processing states to match
the unique challenges of acting and learning in diverse environments and behavioral …

Apitherapy for Parkinson's disease: A focus on the effects of propolis and royal jelly

AM Ali, H Kunugi - Oxidative medicine and cellular longevity, 2020 - Wiley Online Library
The vast increase of world's aging populations is associated with increased risk of age‐
related neurodegenerative diseases such as Parkinson's disease (PD). PD is a widespread …

Nanoparticle-guided brain drug delivery: Expanding the therapeutic approach to neurodegenerative diseases

C Riccardi, F Napolitano, D Montesarchio, S Sampaolo… - Pharmaceutics, 2021 - mdpi.com
Neurodegenerative diseases (NDs) represent a heterogeneous group of aging-related
disorders featured by progressive impairment of motor and/or cognitive functions, often …

Molecular mechanisms underlying the neuroprotection of environmental enrichment in Parkinson's disease

TA Alarcón, SM Presti-Silva, APT Simões… - Neural Regeneration …, 2023 - journals.lww.com
Parkinson's disease is the most common movement disorder, affecting about 1% of the
population over the age of 60 years. Parkinson's disease is characterized clinically by …

Contribution of cholinergic interneurons to striatal pathophysiology in Parkinson's disease

S Ztaou, M Amalric - Neurochemistry international, 2019 - Elsevier
Parkinson's disease (PD) is a neurodegenerative disorder caused by the loss of nigral
dopaminergic neurons innervating the striatum, the main input structure of the basal ganglia …

Pharmacological effects of natural Ganoderma and its extracts on neurological diseases: A comprehensive review

C Zhao, C Zhang, Z Xing, Z Ahmad, JS Li… - International Journal of …, 2019 - Elsevier
Ganoderma, has been used for clinical applications for thousands of years as a highly-
nutritious and significantly-effective medicinal herb. The active components and efficacy of …

Cellular and subcellular localization of Rab10 and phospho-T73 Rab10 in the mouse and human brain

V Singh, MA Menard, GE Serrano, TG Beach… - Acta Neuropathologica …, 2023 - Springer
Autosomal dominant pathogenic mutations in Leucine-rich repeat kinase 2 (LRRK2) cause
Parkinson's disease (PD). The most common mutation, G2019S-LRRK2, increases the …

Protective capacity of carotenoid trans-astaxanthin in rotenone-induced toxicity in Drosophila melanogaster

TC Akinade, OO Babatunde, AO Adedara… - Scientific Reports, 2022 - nature.com
Abstract Trans-astaxanthin (TA), a keto-carotenoid found in aquatic invertebrates, possesses
anti-oxidative and anti-inflammatory activities. Rotenone is used to induce oxidative stress …