[HTML][HTML] Glycomimetics for the inhibition and modulation of lectins

S Leusmann, P Ménová, E Shanin, A Titz… - Chemical Society …, 2023 - pubs.rsc.org
Carbohydrates are essential mediators of many processes in health and disease. They
regulate self-/non-self-discrimination, are key elements of cellular communication, cancer …

Advances in the treatment of inflammatory bowel disease: Focus on polysaccharide nanoparticulate drug delivery systems

H Hadji, K Bouchemal - Advanced Drug Delivery Reviews, 2022 - Elsevier
The complex pathogenesis of inflammatory bowel disease (IBD) explains the several
hurdles for finding an efficient approach to cure it. Nowadays, therapeutic protocols aim to …

[HTML][HTML] Gut microbiota-derived ursodeoxycholic acid from neonatal dairy calves improves intestinal homeostasis and colitis to attenuate extended-spectrum β …

Z He, Y Ma, S Yang, S Zhang, S Liu, J Xiao, Y Wang… - Microbiome, 2022 - Springer
Background Antimicrobials are often used to prevent and treat diarrhea induced by
enteroaggregative Escherichia coli (EAEC) in young ruminants. However, drug overuse or …

[HTML][HTML] Pathobionts in inflammatory bowel disease: origins, underlying mechanisms, and implications for clinical care

A Gilliland, JJ Chan, TJ De Wolfe, H Yang, BA Vallance - Gastroenterology, 2023 - Elsevier
The gut microbiota plays a significant role in the pathogenesis of both forms of inflammatory
bowel disease (IBD), namely Crohn's disease (CD) and ulcerative colitis (UC). While …

The multifaceted virulence of adherent-invasive Escherichia coli

S Mansour, T Asrar, W Elhenawy - Gut Microbes, 2023 - Taylor & Francis
The surge in inflammatory bowel diseases, like Crohn's disease (CD), is alarming. While the
role of the gut microbiome in CD development is unresolved, the frequent isolation of …

[HTML][HTML] Selective antibacterial activity of Citrus Medica limonum essential oil against Escherichia coli K99 and Lactobacillus acidophilus and its antibacterial …

W Tang, Z Zhang, D Nie, S Liu, Y Li, M Liu, Y Zhang… - Lwt, 2023 - Elsevier
Escherichia coli K99 (E. coli K99) is one of the important pathogenic bacteria in calf
production causing massive loss every year, and Lactobacillus acidophilus (L. acidophilus) …

[HTML][HTML] Structural insights into a cooperative switch between one and two FimH bacterial adhesins binding pauci-and high-mannose type N-glycan receptors

EM Krammer, C Bridot, S Serna, B Echeverria… - Journal of Biological …, 2023 - ASBMB
The FimH type-1 fimbrial adhesin allows pathogenic Escherichia coli to adhere to
glycoproteins in the epithelial linings of human bladder and intestinal tract, by using multiple …

From ASCA breakthrough in Crohn's disease and Candida albicans research to thirty years of investigations about their meaning in human health

B Sendid, M Cornu, C Cordier, J Bouckaert… - Autoimmunity …, 2023 - Elsevier
Anti-Saccharomyces cerevisiae antibodies (ASCA) are human antibodies that can be
detected using an enzyme-linked immunosorbent assay involving a mannose polymer …

[HTML][HTML] The oral-gut axis: a missing piece in the IBD puzzle

S Kitamoto, N Kamada - Inflammation and Regeneration, 2023 - Springer
Inflammatory bowel disease (IBD) is a multifactorial intractable intestinal disease. Focusing
on only one facet of the pathogenesis of IBD is insufficient to fully capture the complexity of …

Evidence for a causal role for Escherichia coli strains identified as adherent-invasive (AIEC) in intestinal inflammation

H Kittana, JC Gomes-Neto, K Heck, AF Juritsch… - Msphere, 2023 - Am Soc Microbiol
Enrichment of adherent-invasive Escherichia coli (AIEC) has been consistently detected in
subsets of inflammatory bowel disease (IBD) patients. Although some AIEC strains cause …