Citrus fruits contain numerous antioxidative biomolecules including phenolic acids,
flavonols, flavanones, polymethoxyflavones (PMFs), and their derivatives. Previous in vitro …

Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription factor that regulates the
cellular antioxidant defense system at the posttranscriptional level. During oxidative stress …

Hesperidin (Hsd), a bioactive phytomedicine, experienced an antidiabetic activity versus
both Type 1 and Type 2 Diabetes mellitus. However, its intrinsic poor solubility and …

Diabetes is a chronic metabolic disease characterized by an excess of glucose in the blood.
If the constant sugar level is not managed correctly in diabetic patients, it may lead to …

Evidence supports a strong bidirectional association between depression and Type 2
diabetes mellitus (T2DM). The harmful impact of oxidative stress and chronic inflammation …

Cyclosporine A (CsA) is employed for organ transplantation and autoimmune disorders.
Nephrotoxicity is a serious side effect that hampers the therapeutic use of CsA. Hesperidin …

Introduction Hesperidin is a flavanone glycoside occurring in high levels in citrus species. It
is among the most significant natural anti-oxidants employed often in pharmaceuticals for …

In recent days, various types of LDHs are used for biomedical functions. Due to the unique
structure of LDH, it has a vast area of application. In different biomedical sectors, the …

Introduction Hesperidin (HSP) has multiple beneficial effects in verities of clinical situations
including type 2 diabetes mellitus (T2DM). Aim: Determination of curative effects of HSP on …

Restoring the lost bioelectrical signal transmission along with the appropriate
microenvironment is one of the major clinical challenges in spinal cord regeneration. In the …