Pharmacogenomics: current status and future perspectives

M Pirmohamed - Nature Reviews Genetics, 2023 - nature.com
Inter-individual variability in drug response, be it efficacy or safety, is common and likely to
become an increasing problem globally given the growing elderly population requiring …

Pharmacogenetics of antiplatelet therapy

M Castrichini, JA Luzum… - Annual review of …, 2023 - annualreviews.org
Antiplatelet therapy is used in the treatment of patients with acute coronary syndromes,
stroke, and those undergoing percutaneous coronary intervention. Clopidogrel is the most …

East Asian-specific and cross-ancestry genome-wide meta-analyses provide mechanistic insights into peptic ulcer disease

Y He, M Koido, Y Sutoh, M Shi, Y Otsuka-Yamasaki… - Nature Genetics, 2023 - nature.com
Peptic ulcer disease (PUD) refers to acid-induced injury of the digestive tract, occurring
mainly in the stomach (gastric ulcer (GU)) or duodenum (duodenal ulcer (DU)). In the …

Evaluation of Antiulcer Potentiality of D-Alpha-Tocopheryl Succinate by Inhibition of Oxidative Stress and Proinflammatory Cytokines

V Nimbalkar, N Vyawahare, S Shinde… - … Intelligence for Clinical …, 2023 - Springer
The purpose of this research is to examine the in vitro potentiality of D-α-tocopheryl
succinate for antiulcer activity in a standard dose manner. The current study assessed the …