Network pharmacology provides a systematic approach to understanding the treatment of ischemic heart diseases with traditional Chinese medicine

HY Yang, ML Liu, P Luo, XS Yao, H Zhou - Phytomedicine, 2022 - Elsevier
Background The field of network pharmacology showed significant development. The
concept of network pharmacology has many similarities to the philosophy of traditional …

Chinmedomics, a new strategy for evaluating the therapeutic efficacy of herbal medicines

Y Han, H Sun, A Zhang, G Yan, X Wang - Pharmacology & Therapeutics, 2020 - Elsevier
Herbal medicines have accumulated valuable clinical experience in thousands of years of
applications in traditional Chinese medicine (TCM) or ethnomedicine. The unique multi …

Hydroxysafflor yellow A, a natural compound from Carthamus tinctorius L with good effect of alleviating atherosclerosis

X Xue, Y Deng, J Wang, M Zhou, L Liao, C Wang… - Phytomedicine, 2021 - Elsevier
Background Atherosclerosis is a chronic vascular inflammatory disease with complex
pathogenesis. Its serious consequence is insufficient blood supply to heart and brain, which …

Network pharmacology-based strategy to investigate pharmacological mechanisms of Zuojinwan for treatment of gastritis

G Yu, W Wang, X Wang, M Xu, L Zhang, L Ding… - … and alternative medicine, 2018 - Springer
Background Zuojinwan (ZJW), a classic herbal formula, has been extensively used to treat
gastric symptoms in clinical practice in China for centuries. However, the pharmacological …

Danhong injection in cardiovascular and cerebrovascular diseases: pharmacological actions, molecular mechanisms, and therapeutic potential

X Feng, Y Li, Y Wang, L Li, PJ Little, S Xu… - Pharmacological Research, 2019 - Elsevier
Cardiovascular and cerebrovascular diseases are the main cause of mortality worldwide,
currently with less than optimum therapeutic options. Danhong injection (DHI) is a medicinal …

Pharmacological potential of the combination of Salvia miltiorrhiza (Danshen) and Carthamus tinctorius (Honghua) for diabetes mellitus and its cardiovascular …

JO Orgah, S He, Y Wang, M Jiang, Y Wang… - Pharmacological …, 2020 - Elsevier
Metabolic syndrome, such as diabetes mellitus, obesity, atherosclerosis, and high blood
pressure (HBP), are closely linked pathophysiologically. However, current monotherapies …

Integrated network pharmacology analysis and serum metabolomics to reveal the cognitive improvement effect of Bushen Tiansui formula on Alzheimer's disease

Z Zhang, P Yi, J Yang, J Huang, P Xu, M Hu… - Journal of …, 2020 - Elsevier
Abstract Ethnopharmacological relevance Bushen Tiansui Formula (BSTSF) is a traditional
Chinese medicine formula used clinically to treat Alzheimer's disease (AD) for many years …

[HTML][HTML] Protection against acute cerebral ischemia/reperfusion injury by QiShenYiQi via neuroinflammatory network mobilization

Y Wang, G Xiao, S He, X Liu, L Zhu, X Yang… - Biomedicine & …, 2020 - Elsevier
Cerebral ischemia/reperfusion injury (CI/RI) is a common feature of ischemic stroke,
involving a period of impaired blood supply to the brain, followed by the restoration of …

Uncovering the mechanism of Maxing Ganshi Decoction on asthma from a systematic perspective: A network pharmacology study

W Song, S Ni, Y Fu, Y Wang - Scientific reports, 2018 - nature.com
Abstract Maxing Ganshi Decoction (MXGSD) is used widely for asthma over thousands of
years, but its underlying pharmacological mechanisms remain unclear. In this study …

Targeting inflammation‐associated AMPK//Mfn‐2/MAPKs signaling pathways by baicalein exerts anti‐atherosclerotic action

X Zhang, Y Qin, W Ruan, X Wan, C Lv… - Phytotherapy …, 2021 - Wiley Online Library
Inflammatory responses in macrophages, endothelial cells, and vascular smooth muscle
cells play crucial roles in the development of atherosclerosis. Baicalein, a flavonoid …