1, 2, 3‐Triazole hybrids as anticancer agents: A review
MM Alam - Archiv der Pharmazie, 2022 - Wiley Online Library
Despite the advancements in the development of anticancer agents, more effective and
safer anticancer drugs still need to be developed as the current agents cause unwanted side …
safer anticancer drugs still need to be developed as the current agents cause unwanted side …
Research progress on the synthesis and pharmacology of 1, 3, 4-oxadiazole and 1, 2, 4-oxadiazole derivatives: a mini review
JJ Wang, W Sun, WD Jia, M Bian… - Journal of Enzyme …, 2022 - Taylor & Francis
Oxadiazole is a five-membered heterocyclic compound containing two nitrogen atoms and
one oxygen atom. The 1, 3, 4-oxadiazole and 1, 2, 4-oxadiazole have favourable physical …
one oxygen atom. The 1, 3, 4-oxadiazole and 1, 2, 4-oxadiazole have favourable physical …
Mechanistic Wound Healing and Antioxidant Potential of Moringa oleifera Seeds Extract Supported by Metabolic Profiling, In Silico Network Design, Molecular …
Moringa oleifera Lam.(Moringaceae) is an adaptable plant with promising phytoconstituents,
interesting medicinal uses, and nutritional importance. Chemical profiling of M. oleifera …
interesting medicinal uses, and nutritional importance. Chemical profiling of M. oleifera …
Naproxen based 1, 3, 4-oxadiazole derivatives as EGFR inhibitors: Design, synthesis, anticancer, and computational studies
MM Alam, S Nazreen, ASA Almalki, AA Elhenawy… - Pharmaceuticals, 2021 - mdpi.com
A library of novel naproxen based 1, 3, 4-oxadiazole derivatives (8–16 and 19–26) has been
synthesized and screened for cytotoxicity as EGFR inhibitors. Among the synthesized …
synthesized and screened for cytotoxicity as EGFR inhibitors. Among the synthesized …
Synthesis and biological evaluation of 1, 2, 3-triazole tethered thymol-1, 3, 4-oxadiazole derivatives as anticancer and antimicrobial agents
ASA Almalki, S Nazreen, AM Malebari, NM Ali… - Pharmaceuticals, 2021 - mdpi.com
A library of 1, 2, 3-triazole-incorporated thymol-1, 3, 4-oxadiazole derivatives (6–18)
hasbeen synthesized and tested for anticancer and antimicrobial activities. Compounds 7, 8 …
hasbeen synthesized and tested for anticancer and antimicrobial activities. Compounds 7, 8 …
Synthesis, antiproliferative, docking and DFT studies of benzimidazole derivatives as EGFR inhibitors
HA Alzahrani, MM Alam, AA Elhenawy… - Journal of Molecular …, 2022 - Elsevier
In the present work, new benzimidazole linked 1, 2, 3-triazole hybrids have been
synthesized and screened for antiproliferative and EGFR kinase inhibitory activities. The …
synthesized and screened for antiproliferative and EGFR kinase inhibitory activities. The …
Design, synthesis and molecular docking studies of thymol based 1, 2, 3-triazole hybrids as thymidylate synthase inhibitors and apoptosis inducers against breast …
Natural product produced by plants has been the backbone for numerous anticancer agents.
In the present work, natural bioactive thymol based 1, 2, 3-triazole hybrids have been …
In the present work, natural bioactive thymol based 1, 2, 3-triazole hybrids have been …
Cancer and diabetes: the interlinking metabolic pathways and repurposing actions of antidiabetic drugs
Cancers are regarded as one of the main causes of death and result in high health burden
worldwide. The management of cancer include chemotherapy, surgery and radiotherapy …
worldwide. The management of cancer include chemotherapy, surgery and radiotherapy …
An understanding of mechanism-based approaches for 1, 3, 4-oxadiazole scaffolds as cytotoxic agents and enzyme inhibitors
The world's health system is plagued by cancer and a worldwide effort is underway to find
new drugs to treat cancer. There has been a significant improvement in understanding the …
new drugs to treat cancer. There has been a significant improvement in understanding the …
Synthesis, biological evaluation, and molecular docking of new benzimidazole-1, 2, 3-triazole hybrids as antibacterial and antitumor agents
S Ahmed Saleh Alzahrani, S Nazreen… - Polycyclic Aromatic …, 2023 - Taylor & Francis
A new series of benzimidazole-1, 2, 3-triazole hybrids have been successfully accomplished
by the Click chemistry of different aromatic azides and propargylated benzimidazole (4). The …
by the Click chemistry of different aromatic azides and propargylated benzimidazole (4). The …