Susac syndrome: challenges in the diagnosis and treatment

M Marrodan, MP Fiol, J Correale - Brain, 2022 - academic.oup.com
Susac syndrome is a disorder thought to be mediated by an autoimmune response towards
endothelial cells, leading to a characteristic clinical triad of encephalopathy, visual …

Susac syndrome: a scoping review

C David, K Sacré, MC Henri-Feugeas, I Klein… - Autoimmunity …, 2022 - Elsevier
Susac syndrome is a rare disease characterized by an inflammatory microangiopathy limited
to the brain, eye, and ear vessels. It mainly affects young women. Although the …

Susac syndrome: neurological update (clinical features, long-term observational follow-up and management of sixteen patients)

S Bose, A Papathanasiou, S Karkhanis, JP Appleton… - Journal of …, 2023 - Springer
Susac syndrome is a likely autoimmune microangiopathy affecting the brain, retina and
inner ear. Due to the rarity of this condition, diagnosis and treatment can be challenging …

Mechanisms and Emerging Therapies for Treatment of Seizures in Pediatric Autoimmune Encephalitis and Autoinflammatory/Autoimmune-Associated Epilepsy

MM Andzelm, CM Stredny - Rheumatic Disease Clinics, 2023 - rheumatic.theclinics.com
Although first proposed over a century ago, 1, 2 in the past few decades, there has been an
increasing appreciation of the role of the immune system and inflammation in a Program in …

[HTML][HTML] Tissue-resident CD8 T cells in central nervous system inflammatory diseases: present at the crime scene and… guilty

D Merkler, I Vincenti, F Masson, RS Liblau - Current opinion in immunology, 2022 - Elsevier
Tissue-resident memory T cells (T RM) represent a subset of antigen-experienced T cells
that are constantly retained in a given tissue with limited trafficking through the circulation …

Clinical characteristics and treatment approaches in patients with Susac syndrome: a scoping review of cases

R Stinissen, E Tukanov, M Wyckmans, J Kerstens… - Journal of …, 2023 - Springer
Abstract Background Susac syndrome (SuS) is a rare disease characterized by
encephalopathy, hearing impairment and visual disturbances. Immunosuppressive …

Neuropsychiatric disorders: An immunological perspective

E Aw, Y Zhang, E Yalcin, US Herrmann… - Advances in …, 2021 - Elsevier
Neuropsychiatric diseases have traditionally been studied from brain, and mind-centric
perspectives. However, mounting epidemiological and clinical evidence shows a strong …

[HTML][HTML] Therapeutic potential of natural killer cells in neuroimmunological diseases

Q Zhang, J Lin, M Yang, Z Li, M Zhang, B Bu - Biomedicine & …, 2024 - Elsevier
Natural killer (NK) cells, a major component of the innate immune system, have prominent
immunoregulatory, antitumor proliferation, and antiviral activities. NK cells act as a double …

Susac syndrome with the typical clinical triad: a case report and literature review

K Hu, Y Yang, J Liu, X Chen, C Li, Y Liu, B Yang… - Journal of …, 2022 - Elsevier
Susac syndrome is an immune-mediated microvascular disease characterized by the
clinical triad of acute multiple encephalopathies, branch retinal artery occlusion, and …

KIR3DL1 and Tox identify clonally expanded encephalitogenic neuron-specific CD8+ T cells in autoimmune encephalitis

S Perriot, S Jones, R Genolet, A Mathias, H Lindsay… - bioRxiv, 2024 - biorxiv.org
Autoreactive CD8+ T cells are the principal suspects in autoimmune encephalitis (AIE) with
antibodies targeting intracellular neuronal antigens So far, the search for neuron …