The neurodevelopmental hypothesis of schizophrenia has been highly influential in shaping
our current thinking about modeling the disease in animals. Based on the findings provided …

During recent decades, interest in the prevention of mental illnesses has increased.
Improved diagnostic tools, the advent of atypical antipsychotic medications and the …

Emerging evidence indicates that schizophrenia is associated with activated peripheral and
central inflammatory responses. Such inflammatory processes seem to be influenced by a …

Most mental illnesses emerge during adolescence and early adulthood, with considerable
associated distress and functional decline appearing during this critical developmental …

Based on the epidemiological association between maternal infection during pregnancy and
enhanced risk of neurodevelopmental brain disorders in the offspring, a number of in-vivo …

Aim: Given the growing interest in the study of first‐episode psychosis, clinical and research
programmes would benefit from a conceptual clarification of how to operationalize 'first …

Objective: Over the last 15 years, a focus on early intervention in psychotic disorders has
emerged. Initially, the early psychosis movement focused on timely recognition and phase …

Objective: To evaluate the length of the interval between the onset and the initial
management of bipolar disorder (BD). Method: We conducted a meta-analysis using the …

Context Longitudinal magnetic resonance imaging studies have shown progressive gray
matter reduction in the superior temporal gyrus during the earliest phases of schizophrenia …

Family interventions for psychosis (FIp) are effective in reducing service user relapse and
carer distress in people with schizophrenia-spectrum conditions. Several treatment and best …