Early detection of psychosis: positive effects on 5-year outcome

TK Larsen, I Melle, B Auestad, U Haahr, I Joa… - Psychological …, 2011 - cambridge.org
BackgroundDuring the last decades we have seen a new focus on early treatment of
psychosis. Several reviews have shown that duration of untreated psychosis (DUP) is …

Early intervention in psychotic disorders: detection and treatment of the first episode and the critical early stages

PD McGorry, E Killackey… - Medical Journal of …, 2007 - Wiley Online Library
The two main goals of early intervention in psychotic disorders are to reduce the period of
time between the onset of psychosis and the commencement of effective treatment, and to …

Disease prediction in the at-risk mental state for psychosis using neuroanatomical biomarkers: results from the FePsy study

N Koutsouleris, S Borgwardt… - Schizophrenia …, 2012 - academic.oup.com
Background: Reliable prognostic biomarkers are needed for the early recognition of
psychosis. Recently, multivariate machine learning methods have demonstrated the …

Traditional, complementary, and alternative medicine approaches to mental health care and psychological wellbeing in India and China

J Thirthalli, L Zhou, K Kumar, J Gao, H Vaid… - The Lancet …, 2016 - thelancet.com
India and China face the same challenge of having too few trained psychiatric personnel to
manage effectively the substantial burden of mental illness within their population. At the …

The critical treatment window of clozapine in treatment-resistant schizophrenia: secondary analysis of an observational study

B Yoshimura, Y Yada, R So, M Takaki, N Yamada - Psychiatry research, 2017 - Elsevier
Previous studies have suggested that a delay in initiating clozapine is one of the predictors
of outcomes in treatment-resistant schizophrenia (TRS). However, whether there is a critical …

Transforming the treatment of schizophrenia in the United States: the RAISE initiative

LB Dixon, HH Goldman, VH Srihari… - Annual Review of …, 2018 - annualreviews.org
The schizophrenia spectrum disorders are neurodevelopmental illnesses with a lifetime
prevalence near 1%, producing extensive functional impairment and low expectations for …

Toward personalized medicine in schizophrenia: Genetics and epigenetics of antipsychotic treatment

AJ Lisoway, CC Chen, CC Zai, AK Tiwari… - Schizophrenia …, 2021 - Elsevier
Schizophrenia is a complex psychiatric disorder where genetic, epigenetic, and
environmental factors play a role in disease onset, course of illness, and treatment outcome …

Initiatives to shorten duration of untreated psychosis: systematic review

B Lloyd-Evans, M Crosby, S Stockton… - The British Journal of …, 2011 - cambridge.org
BackgroundLong duration of untreated psychosis (DUP) is common and associated with
poor outcomes. Strategies to enhance early detection of first-episode psychosis have been …

The relationship between the duration of untreated psychosis and outcome in low-and-middle income countries: a systematic review and meta analysis

S Farooq, M Large, O Nielssen, W Waheed - Schizophrenia research, 2009 - Elsevier
BACKGROUND: The duration of untreated psychosis (DUP) is defined as the period
between the onset of symptoms of psychosis and the start of antipsychotic treatment. Delay …

What we know: findings that every theory of schizophrenia should explain

AW MacDonald, SC Schulz - Schizophrenia bulletin, 2009 - academic.oup.com
The article summarizes the process used to distill schizophrenia science into 22 facts. These
facts consist of 6 basic facts, 3 etiological facts, 6 pharmacological and treatment facts, 5 …