Importance In most patients, a prodromal period precedes the onset of schizophrenia.
Although clinical criteria for identifying the psychosis risk syndrome (PRS) show promising …

Cognitive impairment is a common feature of schizophrenia; however, its origin remains
controversial. Neurodevelopmental abnormalities clearly play a role in pre-morbid cognitive …

Mounting evidence implicates microRNAs (miRNAs) in the pathology of schizophrenia.
These small noncoding RNAs bind to mRNAs containing complementary sequences and …

The etiology of schizophrenia has been the focus of intensive research for a long time.
Perspectives have changed drastically with the development of new investigative …

INTRODUCTION: To assess the impact of duration of untreated psychosis (DUP) on
baseline and 18-month follow-up characteristics controlling for relevant confounders in an …

Introduction A psychotic episode may be sufficiently traumatic to induce symptoms of post-
traumatic stress disorder (PTSD), which could impact outcomes in first-episode psychosis …

Aim We examined the efficacy and effectiveness (transfer to functional competence and
everyday functioning) of cognitive remediation in early‐course (within 5 years of first …

BackgroundIn first-episode schizophrenia, longer duration of untreated psychosis (DUP)
predicts poorer outcomes. AimsTo address whether the relationship between DUP and …

Aim Long‐acting injectable antipsychotic drugs (LAIs) are often used as an alternative to
oral antipsychotics (OAPs) in individuals with psychosis who demonstrate poor medication …

The last 20 years have seen an increased focus on early intervention in psychotic disorders
in research and clinical practice. Interventions have typically aimed at either reducing the …