Challenges in the development of soft sensors for bioprocesses: A critical review
Among the greatest challenges in soft sensor development for bioprocesses are variable
process lengths, multiple process phases, and erroneous model inputs due to sensor faults …
process lengths, multiple process phases, and erroneous model inputs due to sensor faults …
[HTML][HTML] A review of ultrasonic sensing and machine learning methods to monitor industrial processes
Supervised machine learning techniques are increasingly being combined with ultrasonic
sensor measurements owing to their strong performance. These techniques also offer …
sensor measurements owing to their strong performance. These techniques also offer …
Designs of continuous-flow pharmaceutical crystallizers: developments and practice
Crystallization is an effective, low-cost purification & formulation process widely applied to
pharmaceuticals and fine chemicals. This review describes recent advances in research on …
pharmaceuticals and fine chemicals. This review describes recent advances in research on …
Quality by control: Towards model predictive control of mammalian cell culture bioprocesses
W Sommeregger, B Sissolak, K Kandra… - Biotechnology …, 2017 - Wiley Online Library
The industrial production of complex biopharmaceuticals using recombinant mammalian cell
lines is still mainly built on a quality by testing approach, which is represented by fixed …
lines is still mainly built on a quality by testing approach, which is represented by fixed …
A critical review of recent trends, and a future perspective of optical spectroscopy as PAT in biopharmaceutical downstream processing
As competition in the biopharmaceutical market gets keener due to the market entry of
biosimilars, process analytical technologies (PATs) play an important role for process …
biosimilars, process analytical technologies (PATs) play an important role for process …
Critical review of real-time methods for solid waste characterisation: Informing material recovery and fuel production
Waste management processes generally represent a significant loss of material, energy and
economic resources, so legislation and financial incentives are being implemented to …
economic resources, so legislation and financial incentives are being implemented to …
Critical review of electronic nose and tongue instruments prospects in pharmaceutical analysis
T Wasilewski, D Migoń, J Gębicki, W Kamysz - Analytica Chimica Acta, 2019 - Elsevier
Electronic nose (enose, EN) and electronic tongue (etongue, ET) have been designed to
simulate human senses of smell and taste in the best possible way. The signals acquired …
simulate human senses of smell and taste in the best possible way. The signals acquired …
Process‐wide control and automation of an integrated continuous manufacturing platform for antibodies
Integrated continuous manufacturing is entering the biopharmaceutical industry. The main
drivers range from improved economics, manufacturing flexibility, and more consistent …
drivers range from improved economics, manufacturing flexibility, and more consistent …
PAT implementation on a mobile continuous pharmaceutical manufacturing system: real-time process monitoring with in-line FTIR and Raman spectroscopy
Y Miyai, A Formosa, C Armstrong… - … Process Research & …, 2021 - ACS Publications
The strategies and experimental methods for implementation of process analytical
technology (PAT) on the mobile pharmaceutical manufacturing system, Pharmacy on …
technology (PAT) on the mobile pharmaceutical manufacturing system, Pharmacy on …
Recent progress of continuous crystallization
T Wang, H Lu, J Wang, Y Xiao, Y Zhou, Y Bao… - Journal of industrial and …, 2017 - Elsevier
Continuous crystallization has always been a hot topic in industrial crystallization. Many
efforts have been made to improve the continuous crystallization, either by designing novel …
efforts have been made to improve the continuous crystallization, either by designing novel …