This study focuses on the production phase of drug development and examines approaches
and their progress indicators for enhancing the quality of pharmaceutical products and …

Real-time analytical tools to monitor bioprocess and fermentation in biological and food
applications are becoming increasingly important. Traditional laboratory-based analyses …

Spectral instruments can be useful for the rapid assessment of chemical compounds in
different targets, and their use have been already reported for the modeling of grape …

The improvements in healthcare systems and the advent of the precision medicine initiative
have created the need to develop more innovative manufacturing methods for the delivery …

In this contribution, a data-driven control approach was developed and applied
experimentally to a pharmaceutical batch cooling crystallization process. In this approach, a …

Reactive crystallization to make cefixime trihydrate crystals via cefixime disodium reacting
with hydrogen chloride was investigated using ATR FTIR and an online imaging instrument …

The impurity effect on the crystal properties, such as particle size and shape distribution, is
significant, having significant impact on the downstream processes as well as on the product …

In recent years, to guarantee a quality-by-design approach to the development of
pharmaceutical products, it is important to identify properties of raw materials and excipients …

Downstream processing or product recovery plays a vital role in the development of
bioprocesses. To improve the bioprocess efficiency, some unconventional methods are …

Technology transfer of a small volume continuous (SVC) process and Current Good
Manufacturing Practices (cGMP) manufacturing of merestinib are described. A hybrid batch …