Mitochondria are well known as organelles responsible for the maintenance of cellular
bioenergetics through the production of ATP. Although oxidative phosphorylation may be …

Idiopathic pulmonary fibrosis (IPF) is a devastating lung disease of unknown etiology. It is
characterized by deposition of extracellular matrix proteins, like collagen and fibronectin in …

Alveolar epithelial–capillary barrier disruption is a hallmark of acute respiratory distress
syndrome (ARDS). Contribution of mitochondrial dysfunction to the compromised alveolar …

The transfer of mitochondria between cells has recently been revealed as a spontaneous
way to protect the injured cells. However, the utilization of this natural transfer process for …

Mitochondrial biology has seen a surge in popularity in the past 5 years, with the emergence
of numerous new avenues of exciting mitochondria-related research including …

As an evolutionarily conserved intracellular degradation pathway, autophagy is essential to
cellular homeostasis. Several studies have demonstrated that autophagy showed an …

Idiopathic pulmonary fibrosis is an incurable disease of unknown etiology. Acute
exacerbation of idiopathic pulmonary fibrosis is associated with high mortality. Excessive …

Background Chronic lung diseases, such as chronic obstructive pulmonary disease (COPD)
and idiopathic pulmonary fibrosis (IPF) are linked to several mitochondrial alterations …

Mitochondria are essential organelles for cell metabolism, growth, and function.
Mitochondria in lung cells have important roles in regulating surfactant production …

Objective To study the regulatory relationship between ozone-induced mitophagy and
pyroptosis in lung epithelial cells. Results First, type I primary alveolar epithelial cells and …