Descending control of nociception in insects?

M Gibbons, S Sarlak, L Chittka - Proceedings of the …, 2022 - royalsocietypublishing.org
Modulation of nociception allows animals to optimize chances of survival by adapting their
behaviour in different contexts. In mammals, this is executed by neurons from the brain and …

[HTML][HTML] A neuropeptidergic circuit gates selective escape behavior of Drosophila larvae

BN Imambocus, F Zhou, A Formozov, A Wittich… - Current Biology, 2022 - cell.com
Animals display selective escape behaviors when faced with environmental threats.
Selection of the appropriate response by the underlying neuronal network is key to …

LabGym: Quantification of user-defined animal behaviors using learning-based holistic assessment

Y Hu, CR Ferrario, AD Maitland, RB Ionides… - Cell Reports …, 2023 - cell.com
Quantifying animal behavior is important for biological research. Identifying behaviors is the
prerequisite of quantifying them. Current computational tools for behavioral quantification …

Nociception in fruit fly larvae

JC Boivin, J Zhu, T Ohyama - Frontiers in Pain Research, 2023 - frontiersin.org
Nociception, the process of encoding and processing noxious or painful stimuli, allows
animals to detect and avoid or escape from potentially life-threatening stimuli. Here, we …

A descending inhibitory mechanism of nociception mediated by an evolutionarily conserved neuropeptide system in Drosophila

I Oikawa, S Kondo, K Hashimoto, A Yoshida… - Elife, 2023 - elifesciences.org
Nociception is a neural process that animals have developed to avoid potentially tissue-
damaging stimuli. While nociception is triggered in the peripheral nervous system, its …

The Drosophila homolog of APP promotes Dscam expression to drive axon terminal growth, revealing interaction between Down syndrome genes

S Pizzano, GR Sterne, MW Veling… - Disease Models & …, 2023 - journals.biologists.com
Down syndrome (DS) is caused by triplication of human chromosome 21 (HSA21). Although
several HSA21 genes have been found to be responsible for aspects of DS, whether and …

Cross-modal modulation gates nociceptive inputs in Drosophila

G Pan, R Li, G Xu, S Weng, X Yang, L Yang, B Ye - Current Biology, 2023 - cell.com
Animals' response to a stimulus in one sensory modality is usually influenced by other
modalities. 1 One important type of multisensory integration is the cross-modal modulation …

Belly roll, a GPI-anchored Ly6 protein, regulates Drosophila melanogaster escape behaviors by modulating the excitability of nociceptive peptidergic interneurons

K Li, Y Tsukasa, M Kurio, K Maeta, A Tsumadori… - ELife, 2023 - elifesciences.org
Appropriate modulation of escape behaviors in response to potentially damaging stimuli is
essential for survival. Although nociceptive circuitry has been studied, it is poorly understood …

A competitive disinhibitory network for robust optic flow processing in Drosophila

M Erginkaya, TL Cruz, M Brotas, K Steck, A Nern… - bioRxiv, 2023 - biorxiv.org
Many animals rely on optic flow for navigation, using differences in eye image velocity to
detect deviations from their intended direction of travel. However, asymmetries in image …

Refinement of a technique for collecting and evaluating the osmolality of haemolymph from Drosophila larvae

M Kurio, Y Tsukasa, T Uemura… - Journal of Experimental …, 2024 - journals.biologists.com
Ex vivo physiological experiments using small insect models such as Drosophila larvae
have become increasingly useful to address fundamental biological questions. To perform …