The gut microbiome in Alzheimer's disease: what we know and what remains to be explored

S Chandra, SS Sisodia, RJ Vassar - Molecular neurodegeneration, 2023 - Springer
Abstract Alzheimer's disease (AD), the most common cause of dementia, results in a
sustained decline in cognition. There are currently few effective disease modifying therapies …

[HTML][HTML] Roles and mechanisms of gut microbiota in patients with Alzheimer's disease

S Wu, X Liu, R Jiang, X Yan, Z Ling - Frontiers in Aging Neuroscience, 2021 - frontiersin.org
Alzheimer's disease (AD) is the most common age-related progressive neurodegenerative
disease, characterized by a decline in cognitive function and neuronal loss, and is caused …

Transmission of Alzheimer's disease-associated microbiota dysbiosis and its impact on cognitive function: evidence from mice and patients

Y Zhang, Y Shen, N Liufu, L Liu, W Li, Z Shi… - Molecular …, 2023 - nature.com
Spouses of Alzheimer's disease (AD) patients are at a higher risk of developing incidental
dementia. However, the causes and underlying mechanism of this clinical observation …

The role of the microbiota-gut-brain axis in the development of Alzheimer's disease

B Wiatrak, K Balon, P Jawień, D Bednarz… - International Journal of …, 2022 - mdpi.com
Along with the increase in life expectancy in the populations of developed and developing
countries resulting from better access and improved health care, the number of patients with …

Short-chain fatty acids in the microbiota–gut–brain axis: role in neurodegenerative disorders and viral infections

A Majumdar, IP Siva Venkatesh… - ACS Chemical …, 2023 - ACS Publications
The gut–brain axis (GBA) is the umbrella term to include all bidirectional communication
between the brain and gastrointestinal (GI) tract in the mammalian body. Evidence from over …

Recent developments in the probiotics as live biotherapeutic products (LBPs) as modulators of gut brain axis related neurological conditions

D Ağagündüz, F Gençer Bingöl, E Çelik… - Journal of Translational …, 2022 - Springer
Probiotics have been defined as “living microorganisms that create health benefits in the
host when taken in sufficient amounts. Recent developments in the understanding of the …

[HTML][HTML] Gut microbiota and its metabolites: bridge of dietary nutrients and Alzheimer's disease

G Zhu, J Zhao, H Zhang, G Wang, W Chen - Advances in Nutrition, 2023 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disease characterized by progressive
cognitive impairment and neuroinflammation. Recent research has revealed the crucial role …

[HTML][HTML] Gut dysbiosis and age-related neurological diseases in females

JM Korf, BP Ganesh, LD McCullough - Neurobiology of disease, 2022 - Elsevier
Historically, females have been underrepresented in biological research. With increased
interest in the gut microbiome and the gut-brain axis, it is important for researchers to pursue …

The gut microbiome regulates astrocyte reaction to Aβ amyloidosis through microglial dependent and independent mechanisms

S Chandra, A Di Meco, HB Dodiya, J Popovic… - Molecular …, 2023 - Springer
Background Previous studies show that antibiotic-mediated (abx) alteration of the gut
microbiome (GMB) results in a reduction of amyloid beta (Aβ) plaques and proinflammatory …

[HTML][HTML] Gut microbiota: critical controller and intervention target in brain aging and cognitive impairment

H Li, J Ni, H Qing - Frontiers in aging neuroscience, 2021 - frontiersin.org
The current trend for the rapid growth of the global aging population poses substantial
challenges for society. The human aging process has been demonstrated to be closely …