[HTML][HTML] Hormone replacement therapy is associated with improved cognition and larger brain volumes in at-risk APOE4 women: results from the European …
Background The risk of dementia is higher in women than men. The metabolic
consequences of estrogen decline during menopause accelerate neuropathology in …
consequences of estrogen decline during menopause accelerate neuropathology in …
[HTML][HTML] lncRNA NEAT1: Key player in neurodegenerative diseases
K Li, Z Wang - Ageing Research Reviews, 2023 - Elsevier
Neurodegenerative diseases are the most common causes of disability worldwide. Given
their high prevalence, devastating symptoms, and lack of definitive diagnostic tests, there is …
their high prevalence, devastating symptoms, and lack of definitive diagnostic tests, there is …
Association of the mediterranean dietary approaches to stop hypertension intervention for neurodegenerative delay (MIND) diet with the risk of dementia
Importance Dementia threatens the well-being of older adults, making efforts toward
prevention of great importance. Objective To evaluate the association of the Mediterranean …
prevention of great importance. Objective To evaluate the association of the Mediterranean …
Neurogenesis in aging and age-related neurodegenerative diseases
Adult neurogenesis, the process by which neurons are generated in certain areas of the
adult brain, declines in an age-dependent manner and is one potential target for extending …
adult brain, declines in an age-dependent manner and is one potential target for extending …
[HTML][HTML] Global and regional spending on dementia care from 2000–2019 and expected future health spending scenarios from 2020–2050: an economic modelling …
P Pedroza, MK Miller-Petrie, C Chen… - …, 2022 - thelancet.com
Background The global burden of dementia is increasing. As diagnosis and treatment rates
increase and populations grow and age, additional diagnosed cases will present a …
increase and populations grow and age, additional diagnosed cases will present a …
[HTML][HTML] Microbiota–gut–brain axis and its therapeutic applications in neurodegenerative diseases
The human gastrointestinal tract is populated with a diverse microbial community. The vast
genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every …
genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every …
[HTML][HTML] Conventional machine learning and deep learning in Alzheimer's disease diagnosis using neuroimaging: A review
Alzheimer's disease (AD) is a neurodegenerative disorder that causes memory degradation
and cognitive function impairment in elderly people. The irreversible and devastating …
and cognitive function impairment in elderly people. The irreversible and devastating …
Sex steroids and the female brain across the lifespan: insights into risk of depression and Alzheimer's disease
Despite widespread sex differences in prevalence and presentation of numerous illnesses
affecting the human brain, there has been little focus on the effect of endocrine ageing. Most …
affecting the human brain, there has been little focus on the effect of endocrine ageing. Most …
Natural polyphenolic nanodots for Alzheimer's disease treatment
The abnormal amyloid‐β accumulation is essential and obbligato in Alzheimer's disease
pathogenesis and natural polyphenols exhibit great potential as amyloid aggregation …
pathogenesis and natural polyphenols exhibit great potential as amyloid aggregation …
[HTML][HTML] Interpretable deep learning translation of GWAS and multi-omics findings to identify pathobiology and drug repurposing in Alzheimer's disease
Translating human genetic findings (genome-wide association studies [GWAS]) to
pathobiology and therapeutic discovery remains a major challenge for Alzheimer's disease …
pathobiology and therapeutic discovery remains a major challenge for Alzheimer's disease …