Antiviral drug resistance of human cytomegalovirus
NS Lurain, S Chou - Clinical microbiology reviews, 2010 - Am Soc Microbiol
The study of human cytomegalovirus (HCMV) antiviral drug resistance has enhanced
knowledge of the virological targets and the mechanisms of antiviral activity. The currently …
knowledge of the virological targets and the mechanisms of antiviral activity. The currently …
[HTML][HTML] CMV: prevention, diagnosis and therapy
CN Kotton - American Journal of Transplantation, 2013 - Elsevier
Cytomegalovirus (CMV) is the most common infection after organ transplantation and has a
major impact on morbidity, mortality and graft survival. Optimal prevention, diagnosis and …
major impact on morbidity, mortality and graft survival. Optimal prevention, diagnosis and …
International consensus guidelines on the management of cytomegalovirus in solid organ transplantation
Cytomegalovirus (CMV) remains one of the most common infections after solid organ
transplantation, resulting in significant morbidity, graft loss, and occasional mortality …
transplantation, resulting in significant morbidity, graft loss, and occasional mortality …
Antiviral drug resistance: mechanisms and clinical implications
L Strasfeld, S Chou - Infectious Disease Clinics, 2010 - id.theclinics.com
In the setting of intensive immunosuppression for the management of rejection in solid organ
transplant (SOT) recipients, or graft-versus-host disease (GVHD) in hematopoietic stem cell …
transplant (SOT) recipients, or graft-versus-host disease (GVHD) in hematopoietic stem cell …
[HTML][HTML] Human cytomegalovirus latency and reactivation in allogeneic hematopoietic stem cell transplant recipients
L Stern, B Withers, S Avdic, D Gottlieb… - Frontiers in …, 2019 - frontiersin.org
Human cytomegalovirus (HCMV) reactivation is a major infectious cause of morbidity and
mortality after allogeneic hematopoietic stem cell transplantation (HSCT). HCMV is a …
mortality after allogeneic hematopoietic stem cell transplantation (HSCT). HCMV is a …
How I treat resistant cytomegalovirus infection in hematopoietic cell transplantation recipients
F El Chaer, DP Shah… - Blood, The Journal of the …, 2016 - ashpublications.org
Cytomegalovirus (CMV) infection is a significant complication in hematopoietic cell
transplantation (HCT) recipients. Four antiviral drugs are used for preventing or treating …
transplantation (HCT) recipients. Four antiviral drugs are used for preventing or treating …
Clinical development of letermovir and maribavir: Overview of human cytomegalovirus drug resistance
The prevention and treatment of human cytomegalovirus (HCMV) infections is based on the
use of antiviral agents that currently target the viral DNA polymerase and that may cause …
use of antiviral agents that currently target the viral DNA polymerase and that may cause …
Cytomegalovirus UL97 mutations in the era of ganciclovir and maribavir
S Chou - Reviews in medical virology, 2008 - Wiley Online Library
Mutations in the human CMV UL97 kinase gene are a major mechanism of viral resistance
to two anti‐CMV drugs, ganciclovir (GCV) and maribavir (MBV). GCV, the most widely used …
to two anti‐CMV drugs, ganciclovir (GCV) and maribavir (MBV). GCV, the most widely used …
Herpesvirus DNA polymerases: Structures, functions and inhibitors
Human herpesviruses are large double-stranded DNA viruses belonging to the
Herpesviridae family. These viruses have the ability to establish lifelong latency into the host …
Herpesviridae family. These viruses have the ability to establish lifelong latency into the host …
Artesunate as a potent antiviral agent in a patient with late drug-resistant cytomegalovirus infection after hematopoietic stem cell transplantation
MY Shapira, IB Resnick, S Chou… - Clinical Infectious …, 2008 - academic.oup.com
This is the first report of treatment of cytomegalovirus infection with artesunate, for a stem cell
transplant recipient with a newly identified foscarnet-resistant and ganciclovir-resistant DNA …
transplant recipient with a newly identified foscarnet-resistant and ganciclovir-resistant DNA …