Metabolic syndrome, haemostasis and thrombosis

MC Alessi, I Juhan-Vague - Thrombosis and haemostasis, 2008 - thieme-connect.com
The metabolic syndrome (metS), a concurrence of abdominal fat, disturbed glucose and
insulin metabolism, dyslipidemia, and hypertension has been strongly associated not only …

Postprandial plasma glucose is an independent risk factor for increased carotid intima-media thickness in non-diabetic individuals

M Hanefeld, C Koehler, F Schaper, K Fuecker… - Atherosclerosis, 1999 - Elsevier
Postprandial (pp) hyperglycemia—frequently associated with an increase in cardiovascular
risk factors—may be damaging for the endothelium. So far, little information exists how …

Beneficial effects of metformin on haemostasis and vascular function in man

PJ Grant - Diabetes & metabolism, 2003 - Elsevier
Type 2 diabetes is characterised by insulin resistance in association with clustering of
atherothrombotic risk factors (dysglycaemia, hyperinsulinaemia, hypertension, raised …

Insulin resistance and C‐reactive protein as independent risk factors for non‐alcoholic fatty liver disease in non‐obese Asian men

SH Park, BIK Kim, JW Yun, JW Kim… - Journal of …, 2004 - Wiley Online Library
Abstract Background and Aim: Although insulin resistance is often considered the link
between obesity and non‐alcoholic fatty liver disease (NAFLD), the role of insulin …

Metabolic syndrome modifies the cardiovascular risk associated with angiographic coronary artery disease in women: a report from the Women's Ischemia Syndrome …

OC Marroquin, KE Kip, DE Kelley, BD Johnson… - Circulation, 2004 - Am Heart Assoc
Background—The metabolic syndrome, which is characterized by a constellation of fasting
hyperglycemia, hypertriglyceridemia, low HDL cholesterol, hypertension, and/or abdominal …

Metformin therapy is associated with a decrease in plasma plasminogen activator inhibitor-1, lipoprotein (a), and immunoreactive insulin levels in patients with the …

EM Velazquez, SG Mendoza, P Wang, CJ Glueck - Metabolism, 1997 - Elsevier
Sixteen nondiabetic women with polycystic ovary syndrome (PCOS) aged 18 to 33 years
were studied before and after 8 weeks on metformin (1.5 g/d) therapy to assess whether …

Association between obesity and a prothrombotic state: the Framingham Offspring Study

GA Rosito, RB D'Agostino, J Massaro… - Thrombosis and …, 2004 - thieme-connect.com
Although obesity is associated with increased cardiovascular risk, the mechanism has not
been fully explained. Since thrombosis is a critical component of cardiovascular disease, we …

Effects of changes in body weight and insulin resistance on inflammation and endothelial function in morbid obesity after bariatric surgery

LA Vázquez, F Pazos, JR Berrazueta… - The Journal of …, 2005 - academic.oup.com
Metabolic alterations such as insulin resistance are thought to underlie the endothelial
dysfunction and low grade inflammation found in morbid obesity. Twenty-six morbidly obese …

Short-term oestrogen replacement therapy improves insulin resistance, lipids and fibrinolysis in postmenopausal women with NIDDM

HE Brussaard, JAG Leuven, M Frölich, C Kluft… - Diabetologia, 1997 - Springer
Oestrogen replacement therapy is associated with a decreased risk of cardiovascular
disease in postmenopausal women. Patients with non-insulin-dependent diabetes mellitus …

Childhood social circumstances and psychosocial and behavioural factors as determinants of plasma fibrinogen

E Brunner, M Marmot, R Canner, M Beksinska… - The Lancet, 1996 - Elsevier
Background High plasma fibrinogen concentration is associated with an increased risk of
coronary heart disease. We have investigated associations between plasma fibrinogen and …