Left Atrial Structure and Function, and Left Ventricular Diastolic Dysfunction: JACC State-of-the-Art Review

L Thomas, TH Marwick, BA Popescu, E Donal… - Journal of the American …, 2019 - jacc.org
Defining left atrial (LA) function has recently emerged as a powerful parameter, particularly
in evaluation of left ventricular (LV) diastolic dysfunction (LVDD) and heart failure with …

Atrial Failure as a Clinical Entity: JACC Review Topic of the Week

F Bisbal, A Baranchuk, E Braunwald… - Journal of the American …, 2020 - jacc.org
Atrial dysfunction has been widely considered a marker or consequence of other cardiac
conditions rather than the cause itself. Here, we propose the term atrial failure as a clinically …

Heart failure with preserved ejection fraction: from mechanisms to therapies

CSP Lam, AA Voors, RA de Boer… - European heart …, 2018 - academic.oup.com
This review aims to provide a translational perspective on recent developments in heart
failure with preserved ejection fraction (HFpEF), linking mechanistic insights to potential …

The pathophysiology of heart failure with preserved ejection fraction

BA Borlaug - Nature Reviews Cardiology, 2014 - nature.com
Approximately half of all patients with heart failure have preserved ejection fraction (HFpEF)
and, as life expectancies continue to increase in western societies, the prevalence of HFpEF …

Beyond ejection fraction: an integrative approach for assessment of cardiac structure and function in heart failure

M Cikes, SD Solomon - European heart journal, 2016 - academic.oup.com
Left ventricular ejection fraction (LVEF) has been the central parameter used for diagnosis
and management in patients with heart failure. A good predictor of adverse outcomes in …

Left atrial remodeling and function in advanced heart failure with preserved or reduced ejection fraction

V Melenovsky, SJ Hwang, MM Redfield… - Circulation: Heart …, 2015 - Am Heart Assoc
Background—Left atrial (LA) structure and function are altered in most heart failure (HF)
patients, but there may be fundamental differences in LA properties between HF with …

Impaired left atrial function in heart failure with preserved ejection fraction

ABS Santos, E Kraigher‐Krainer… - European journal of …, 2014 - Wiley Online Library
Aims Left atrial (LA) enlargement is present in the majority of heart failure with preserved
ejection fraction (HFpEF) patients and is a marker of risk. However, the importance of LA …

Left atrial function: pathophysiology, echocardiographic assessment, and clinical applications

M Roşca, P Lancellotti, BA Popescu, LA Piérard - Heart, 2011 - heart.bmj.com
Atrial function, in a close interdependence with left ventricular (LV) function, plays a key role
in maintaining an optimal cardiac performance. The left atrium (LA) modulates LV filling …

Heart failure with preserved ejection fraction: a comprehensive review and update of diagnosis, pathophysiology, treatment, and perioperative implications

PS Pagel, JN Tawil, BT Boettcher, DA Izquierdo… - Journal of cardiothoracic …, 2021 - Elsevier
Almost three-quarters of all heart failure patients who are older than 65 have heart failure
with preserved ejection fraction (HFpEF). The proportion and hospitalization rate of patients …

Association of CMR-measured LA function with heart failure development: results from the MESA study

M Habibi, H Chahal, A Opdahl, O Gjesdal… - JACC: Cardiovascular …, 2014 - jacc.org
Objectives: The goal of this study was to assess the association between left atrial (LA)
volume and function measured with feature-tracking cardiac magnetic resonance (CMR) …