Necroptosis molecular mechanisms: Recent findings regarding novel necroptosis regulators
Necroptosis is a form of programmed necrosis that is mediated by various cytokines and
pattern recognition receptors (PRRs). Cells dying by necroptosis show necrotic phenotypes …
pattern recognition receptors (PRRs). Cells dying by necroptosis show necrotic phenotypes …
Lytic cell death in metabolic liver disease
Regulated cell death is intrinsically associated with inflammatory liver disease and is pivotal
in governing outcomes of metabolic liver disease. Different types of cell death may coexist …
in governing outcomes of metabolic liver disease. Different types of cell death may coexist …
Oxidative stress‐mediated blood‐brain barrier (BBB) disruption in neurological diseases
K Song, Y Li, H Zhang, N An, Y Wei… - Oxidative medicine …, 2020 - Wiley Online Library
The blood‐brain barrier (BBB), as a crucial gate of brain‐blood molecular exchange, is
involved in the pathogenesis of multiple neurological diseases. Oxidative stress is caused …
involved in the pathogenesis of multiple neurological diseases. Oxidative stress is caused …
The regulation of necroptosis by post-translational modifications
Necroptosis is a caspase-independent, lytic form of programmed cell death whose errant
activation has been widely implicated in many pathologies. The pathway relies on the …
activation has been widely implicated in many pathologies. The pathway relies on the …
Research trends, hot spots and prospects for necroptosis in the field of neuroscience
WT Yan, S Lu, YD Yang, WY Ning, Y Cai… - Neural regeneration …, 2021 - journals.lww.com
There are two types of cell death-apoptosis and necrosis. Apoptosis is cell death regulated
by cell signaling pathways, while necrosis has until recently been considered a passive …
by cell signaling pathways, while necrosis has until recently been considered a passive …
A necroptosis-related lncRNA-based signature to predict prognosis and probe molecular characteristics of stomach adenocarcinoma
L Luo, L Li, L Liu, Z Feng, Q Zeng, X Shu, Y Cao… - Frontiers in …, 2022 - frontiersin.org
Background: As a caspase-independent type of cell death, necroptosis plays a significant
role in the initiation, and progression of gastric cancer (GC). Numerous studies have …
role in the initiation, and progression of gastric cancer (GC). Numerous studies have …
Necroptosis: a pathogenic negotiator in human diseases
Over the past few decades, mechanisms of programmed cell death have attracted the
scientific community because they are involved in diverse human diseases. Initially …
scientific community because they are involved in diverse human diseases. Initially …
Location, location, location: A compartmentalized view of TNF-induced necroptotic signaling
Necroptosis is a lytic, proinflammatory cell death pathway, which has been implicated in host
defense and, when dysregulated, the pathology of many human diseases. The central …
defense and, when dysregulated, the pathology of many human diseases. The central …
Comprehensive analysis of necroptosis-related long noncoding RNA immune infiltration and prediction of prognosis in patients with colon cancer
L Liu, L Huang, W Chen, G Zhang, Y Li… - Frontiers in molecular …, 2022 - frontiersin.org
Colon cancer (CC) is one of the most frequent malignancies in the world, with a high rate of
morbidity and death. In CC, necroptosis and long noncoding RNA (lncRNAs) are crucial, but …
morbidity and death. In CC, necroptosis and long noncoding RNA (lncRNAs) are crucial, but …
Types of necroinflammation, the effect of cell death modalities on sterile inflammation
Distinct types of immune responses are activated by infections, which cause the
development of type I, II, or III inflammation, regulated by Th1, Th2, Th17 helper T cells and …
development of type I, II, or III inflammation, regulated by Th1, Th2, Th17 helper T cells and …