Cellular and molecular mechanisms of kidney fibrosis
Renal fibrosis is the final pathological process common to any ongoing, chronic kidney
injury or maladaptive repair. It is considered as the underlying pathological process of …
injury or maladaptive repair. It is considered as the underlying pathological process of …
[HTML][HTML] Sympathetic nervous system activation and heart failure: Current state of evidence and the pathophysiology in the light of novel biomarkers
JA Borovac, D D'Amario, J Bozic… - World journal of …, 2020 - ncbi.nlm.nih.gov
Heart failure (HF) is a complex clinical syndrome characterized by the activation of at least
several neurohumoral pathways that have a common role in maintaining cardiac output and …
several neurohumoral pathways that have a common role in maintaining cardiac output and …
Lasso peptides: structure, function, biosynthesis, and engineering
MO Maksimov, SJ Pan, AJ Link - Natural product reports, 2012 - pubs.rsc.org
Covering: up to May 2012 Lasso peptides are a class of ribosomally-synthesized and
posttranslationally-modified natural products with diverse bioactivities. This review describes …
posttranslationally-modified natural products with diverse bioactivities. This review describes …
[HTML][HTML] Neuroinflammation and infection: molecular mechanisms associated with dysfunction of neurovascular unit
A Tohidpour, AV Morgun, EB Boitsova… - Frontiers in cellular …, 2017 - frontiersin.org
Neuroinflammation is a complex inflammatory process in the central nervous system, which
is sought to play an important defensive role against various pathogens, toxins or factors that …
is sought to play an important defensive role against various pathogens, toxins or factors that …
COPD as an endothelial disorder: endothelial injury linking lesions in the lungs and other organs?(2017 Grover Conference Series)
Chronic obstructive pulmonary disease (COPD) is characterized by chronic expiratory
airflow obstruction that is not fully reversible. COPD patients develop varying degrees of …
airflow obstruction that is not fully reversible. COPD patients develop varying degrees of …
Proliferating cholangiocytes: a neuroendocrine compartment in the diseased liver
In the last 15 years, the intrahepatic biliary tree has become the object of extensive studies,
which highlighted the extraordinary biologic properties of cholangiocytes involved in bile …
which highlighted the extraordinary biologic properties of cholangiocytes involved in bile …
Endothelin
Y Kawanabe, SM Nauli - Cellular and Molecular Life Sciences, 2011 - Springer
Endothelin-1 is the most potent vasoconstrictor agent currently identified, and it was
originally isolated and characterized from the culture media of aortic endothelial cells. Two …
originally isolated and characterized from the culture media of aortic endothelial cells. Two …
Vascular smooth muscle cell proliferation as a therapeutic target. Part 1: molecular targets and pathways
Cardiovascular diseases are a major cause of human death worldwide. Excessive
proliferation of vascular smooth muscle cells contributes to the etiology of such diseases …
proliferation of vascular smooth muscle cells contributes to the etiology of such diseases …
Endothelin receptor blockers in cardiovascular disease
S Rich, VV McLaughlin - Circulation, 2003 - Am Heart Assoc
The endothelin (ET) system is comprised of 4 active ETs, with ET-1 being the predominant
isoform in the cardiovascular system. Because of the potent vasoconstricting and mitogenic …
isoform in the cardiovascular system. Because of the potent vasoconstricting and mitogenic …
[HTML][HTML] The relationship of stress and blood pressure effectors
Exaggerated cardiovascular response to acute and chronic stresses increases the risk for
hypertension and cardiovascular disease. Stress also can be broadly defined as a …
hypertension and cardiovascular disease. Stress also can be broadly defined as a …