[HTML][HTML] Understanding the Immunopathology of HTLV-1-Associated Adult T-Cell Leukemia/Lymphoma: A Comprehensive Review
S Nakahata, D Enriquez-Vera, MI Jahan, K Sugata… - Biomolecules, 2023 - mdpi.com
Human T-cell leukemia virus type-1 (HTLV-1) causes adult T-cell leukemia/lymphoma (ATL).
HTLV-1 carriers have a lifelong asymptomatic balance between infected cells and host …
HTLV-1 carriers have a lifelong asymptomatic balance between infected cells and host …
[HTML][HTML] The roles of FHL3 in cancer
Z Huang, C Yu, L Yu, H Shu, X Zhu - Frontiers in Oncology, 2022 - frontiersin.org
The four and a half LIM domain protein 3, also named the LIM-protein FHL3, belongs to the
LIM-only family. Based on the special structure of LIM-only proteins, FHL3 can perform …
LIM-only family. Based on the special structure of LIM-only proteins, FHL3 can perform …
[HTML][HTML] Primary cells from patients with adult T cell leukemia/lymphoma depend on HTLV-1 Tax expression for NF-κB activation and survival
R Hleihel, H Skayneh, H de Thé, O Hermine… - Blood Cancer …, 2023 - nature.com
Adult T cell leukemia/lymphoma (ATL) is an aggressive malignancy secondary to chronic
infection with human T cell leukemia virus type 1 (HTLV-1). The viral oncoprotein Tax …
infection with human T cell leukemia virus type 1 (HTLV-1). The viral oncoprotein Tax …
[HTML][HTML] Interplay between innate immunity and the viral oncoproteins Tax and HBZ in the pathogenesis and therapeutic response of HTLV-1 associated adult T cell …
H El Hajj, A Bazarbachi - Frontiers in Immunology, 2022 - frontiersin.org
The Human T-cell Leukemia virus type 1 (HTLV-1) causes an array of pathologies, the most
aggressive of which is adult T-cell leukemia (ATL), a fatal blood malignancy with dismal …
aggressive of which is adult T-cell leukemia (ATL), a fatal blood malignancy with dismal …
[HTML][HTML] Oncoviruses: how do they hijack their host and current treatment regimes
Viruses have the ability to modulate the cellular machinery of their host to ensure their
survival. While humans encounter numerous viruses daily, only a select few can lead to …
survival. While humans encounter numerous viruses daily, only a select few can lead to …
The unique activity of saponin: Induction of cytotoxicity in HTLV-1 infected cells
W Shida, Y Tahara, S Morikawa, K Monde… - Bioorganic & Medicinal …, 2023 - Elsevier
Infection with the retrovirus human T-cell leukemia virus type 1 (HTLV-1) sometimes causes
diseases that are difficult to cure. To find anti-HTLV-1 natural compounds, we opted to …
diseases that are difficult to cure. To find anti-HTLV-1 natural compounds, we opted to …
Momordica charantia phytoconstituents can inhibit human T-lymphotropic virus type-1 (HTLV-1) infectivity in vitro and in vivo
S Ahmadi Ghezeldasht, HR Bidkhori, R Miri… - Journal of …, 2023 - Springer
There is an urgent need to find an effective therapy for life-threatening HTLV-1-associated
diseases. Bitter melon (Momordica charantia) is considered a traditional herb with antiviral …
diseases. Bitter melon (Momordica charantia) is considered a traditional herb with antiviral …
[HTML][HTML] Prediction of the adult T-cell leukemia inhibitory activity of blueberry leaves/stems using direct-injection electron ionization-mass spectrometry metabolomics
H Kai, Y Okada, Y Goto, T Nakayama, K Sugamoto… - Plants, 2022 - mdpi.com
Although Vaccinium virgatum Aiton leaves and stems inhibit adult T-cell leukemia (ATL)
cells, leaves and stems can differ between individual plants and by time and location. In this …
cells, leaves and stems can differ between individual plants and by time and location. In this …
Pivotal role of dihydroorotate dehydrogenase as a therapeutic target in adult T‐cell leukemia
C Ishikawa, N Mori - European Journal of Haematology, 2024 - Wiley Online Library
Objectives We aimed to determine the role of dihydroorotate dehydrogenase (DHODH) in
pathogenesis of adult T‐cell leukemia (ATL) caused by human T‐cell leukemia virus type 1 …
pathogenesis of adult T‐cell leukemia (ATL) caused by human T‐cell leukemia virus type 1 …
Inhibitory effect of a neddylation blockade on HTLV-1-infected T cells via modulation of NF-κB, AP-1, and Akt signaling
C Ishikawa, N Mori - Leukemia & Lymphoma, 2024 - Taylor & Francis
Adult T-cell leukemia (ATL), caused by HTLV-1, is the most lethal hematological malignancy.
NEDD8-activating enzyme (NAE) is a component of the NEDD8 conjunction pathway that …
NEDD8-activating enzyme (NAE) is a component of the NEDD8 conjunction pathway that …