The critical role of neutrophil-endothelial cell interactions in sepsis: new synergistic approaches employing Organ-on-Chip, omics, immune cell phenotyping and in …

D Liu, JC Langston, B Prabhakarpandian… - Frontiers in Cellular …, 2024 - frontiersin.org
Sepsis is a global health concern accounting for more than 1 in 5 deaths worldwide. Sepsis
is now defined as life-threatening organ dysfunction caused by a dysregulated host …

Multi-omics endotypes in ICU sepsis-induced immunosuppression

A Garduno, R Cusack, M Leone, S Einav… - Microorganisms, 2023 - mdpi.com
It is evident that the admission of some patients with sepsis and septic shock to hospitals is
occurring late in their illness, which has contributed to the increase in poor outcomes and …

Mechanisms of Sepsis-Induced Acute Lung Injury and Advancements of Natural Small Molecules in Its Treatment

Y Xu, J Xin, Y Sun, X Wang, L Sun, F Zhao, C Niu… - Pharmaceuticals, 2024 - mdpi.com
Sepsis-induced acute lung injury (ALI), characterized by widespread lung dysfunction, is
associated with significant morbidity and mortality due to the lack of effective …

Predictive role of glycocalyx components and MMP-9 in cardiopulmonary bypass patients for ICU stay

L Lin, M Niu, W Gao, C Wang, Q Wu, F Fang, Y Wang… - Heliyon, 2024 - cell.com
Background Shedding of glycocalyx is relevant to worse prognosis in surgical patients, and
elevated levels of serum matrix metalloproteinase-9 (MMP-9) are associated with this …

[HTML][HTML] 血管内皮屏障功能损伤在疾病中的研究进展

李旭璐, 吴斐华 - Pharmacy Information, 2024 - hanspub.org
许多疾病都具有血管渗漏的共同特征, 内皮屏障功能损伤通常是其根本原因.
内皮屏障是内皮细胞在血管腔和血管壁之间形成的独特屏障, 具有选择性透过作用, 对维持血管 …

Case report: Catastrophic event: neonatal gastric perforation and complication of capillary leak syndrome

J Li, H Lu, LJ Yu, H Li, X Chen, C Chen, E Tao - Frontiers in Pediatrics, 2023 - frontiersin.org
Neonatal gastric perforation (NGP) is a rare, but life-threatening condition that can lead to
serious conditions, such as capillary leak syndrome (CLS). Here, we present the case of a …

[PDF][PDF] Identificación de los mecanismos epigenéticos relacionados con los fenómenos de inmunosupresión en sepsis y su uso como biomarcadores de pronóstico

RO Verdegal, FV Pallardó, JL García - 2023 - roderic.uv.es
TesisROV _ FULL _ v3.2 Page 1 Identificación de los mecanismos epigenéticos relacionados
con los fenómenos de inmunosupresión en sepsis y su uso como biomarcadores de pronóstico …

[PDF][PDF] Newer Insights in Etiology and Pathogenesis of Neonatal Sepsis

I Palić, A Djordjević-Vujičić, D Palić - sciencevolks.com
Neonatal sepsis is a pathophysiological response to the presence of microorganisms or
their toxins in the blood during the first 28 days of life. Despite advances in neonatal …