4,711,783 12/1987 Hue et a1, ________ __ 424/460 thereof, Where the solids or liquids are
useful in the treat 4,716,964 1/1988 Erbstoesser et al. 166/284 ment of the Well or of the …

(60) Provisional application No. 61/505,091, filed on Jul. Controlled Release, 79 (1-3): 1-5.*
6, 2011, provisional application No. 61/585,639, filed Fox (2009)“Squalene Emulsions for …

2016-07-06 Assigned to NOVARTIS VACCINES AND DIAGNOSTICS, INC. reassignment
NOVARTIS VACCINES AND DIAGNOSTICS, INC. ASSIGNMENT OF ASSIGNORS …

Methods and apparatus of embodiments of the invention are adapted to treat tissue inside a
patient's body. Aspects of the invention can be used in a wide variety of applications, but …

The present invention provides for the needleless delivery of selected agents to target
tissues within a subject body by providing the agents in one or more high-energy jets or …

the invention relates to the use of adjuvant compositions comprising type 1 interferon
inducers, such as double-stranded RNA, in combination with antigen delivery systems …

5,294,441. A 3/1994 Curtiss III.......... 424/200.1 he present invention provides methods of
producing pro 5,294.548 A 3/1994 McLinden et al........ 435/235.1 tein in a recombinant …

(57) ABSTRACT A transcutaneous immunization System where the topical application of an
adjuvant and an antigen or nucleic acid encoding for an antigen, to intact skin induces a …

A drug-delivery tool and method for delivering a diagnostic or therapeutic agent to a target
site within a selected body tissue, such as the myocardium of the heart, is disclosed. The …

Disclosed and claimed are methods of non-invasive immunization and drug delivery in an
animal and/or methods of inducing a systemic immune or therapeutic response in an animal …