Bioactive components in whole grains for the regulation of skeletal muscle function

Q Li, H Yang, S Song, J Liu, Z Wang, J Wang - Foods, 2022 - mdpi.com
Skeletal muscle plays a primary role in metabolic health and physical performance.
Conversely, skeletal muscle dysfunctions such as muscular dystrophy, atrophy and aging …

Targeting mitochondrial quality control in muscle aging: Natural dietary products as potential interventions

Q Chen, W Huang, E Capanoglu, AT Amrouche… - Food …, 2023 - Wiley Online Library
Mitochondria are the main sources of energy production for muscle tissues, including
skeletal, cardiac, or smooth muscle, to support their activities. Mitochondrial dysfunction and …

Network Pharmacology/Metabolomics‐Based Validation of AMPK and PI3K/AKT Signaling Pathway as a Central Role of Shengqi Fuzheng Injection Regulation of …

W Guo, S Liu, X Zheng, Z Xiao, H Chen… - Oxidative Medicine …, 2021 - Wiley Online Library
Chinese herbal medicines have multiple targets and properties, and their use in
multidisciplinary cancer therapies has consequently received increasing attention. Here, we …

Gastrodin ameliorates exercise-induced fatigue via modulating Nrf2 pathway and inhibiting inflammation in mice

Y Zhou, Q Wu, W Yu, F Ye, Y Cao, OD Akan, X Wu… - Food Bioscience, 2023 - Elsevier
Gastrodia elata Bl. is traditional Chinese medicine used to alleviate fatigue, but its
underlying mechanism is still unclear. This study explored the anti-fatigue mechanism of …

Gamma-oryzanol alleviates intervertebral disc degeneration development by intercepting the IL-1β/NLRP3 inflammasome positive cycle

H Xu, ZH Dai, GL He, HC Cai, XY Chen, YL Chen, C Xu… - Phytomedicine, 2022 - Elsevier
Background Intervertebral disc degeneration (IVDD) is a highly prevalent musculoskeletal
disorder characterized by a local inflammatory response associated with the IL-1β/NLRP3 …

[HTML][HTML] Molecular targets of exercise mimetics and their natural activators

YJ Jang, S Byun - BMB reports, 2021 - ncbi.nlm.nih.gov
Physical exercise can be effective in preventing or ameliorating various diseases, including
diabetes, cardiovascular diseases, neurodegenerative diseases, and cancer. However, not …

[HTML][HTML] Dark tea extract attenuates age-related muscle loss by suppressing oxidative stress and inflammation in skeletal muscle of mice

A Yoo, HD Seo, JH Hahm, CH Jung, J Ahn… - Journal of Functional …, 2024 - Elsevier
Dark tea (DT), a tea post-fermented by the Eurotium cristatum fungus, is known to attenuate
oxidative damage and chronic inflammation. It also extends the lifespan of Caenorhabditis …

Gamma-oryzanol alleviates osteoarthritis development by targeting Keap1–Nrf2 binding to interfere with chondrocyte ferroptosis

ZH Dai, CC Zhou, CY Yu, CJ Qian, SQ Jin… - International …, 2024 - Elsevier
Osteoarthritis (OA) is a prevalent joint disorder pathologically correlated to chondrocyte
ferroptosis. Gamma-oryzanol (γ-Ory), as a first-line drug for autonomic disorders, aroused …

Antioxidants Supplementation During Exercise: Friends or Enemies for Cardiovascular Homeostasis?

H Wang, Z Yang, X Zhang, J Xie, Y Xie… - Journal of …, 2023 - Springer
Exercise is a preferred strategy for improving cardiac function, especially for patients with
cardiovascular diseases. Increasing evidence indicates that oxidative stress is involved in …

Cycloartenyl ferulate is the predominant compound in brown rice conferring cytoprotective potential against oxidative stress-induced cytotoxicity

H Wu, T Nakamura, Y Guo, R Matsumoto… - International journal of …, 2023 - mdpi.com
Since brown rice extract is a rich source of biologically active compounds, the present study
is aimed to quantify the major compounds in brown rice and to compare their cytoprotective …