Elevated inflammation is a risk factor for many psychiatric (eg, depression) and somatic
conditions (eg, rheumatoid arthritis). Inflammation is influenced by psychosocial processes …

Given that available antidepressant pharmacotherapies are not optimally effective, there is a
need for alternative treatment options that are rooted in a comprehensive understanding of …

Background Scar models posit that heightened anxiety and depression can increase the risk
for subsequent reduced executive function (EF) through increased inflammation across …

A growing body of evidence suggests that rumination, or focused attention on mental
representations of negative events, may have physiological consequences that adversely …

Previous studies have shown that the behavioral inhibition/activation systems (BIS/BAS)
have substantial effects on substance use disorder and emotional disorders, and substance …

Objective Non-suicidal self-injury (NSSI) is prevalent and especially among the adolescence
population. It has been argued that abnormal brain activations in reward processing could …

Inflammation is associated with both lower and higher activity in brain regions that process
rewarding stimuli. How can both low and high sensitivity to rewards be associated with …

An array of negative psychological states–including depressive symptoms, perceived stress,
rumination, and negative affect–have been linked to immune function and inflammatory …

Most research testing the association between inflammation and health outcomes (eg, heart
disease, diabetes, depression) has focused on individual proteins; however, some studies …

Bipolar spectrum disorders are characterized by alternating intervals of extreme positive and
negative affect. We performed a meta-analysis to test the hypothesis that such disorders …