Novel imaging techniques for cystic fibrosis lung disease
JL Goralski, NJ Stewart, JC Woods - Pediatric pulmonology, 2021 - Wiley Online Library
With an increasing number of patients with cystic fibrosis (CF) receiving highly effective
CFTR (cystic fibrosis transmembrane regulator protein) modulator therapy, particularly at a …
CFTR (cystic fibrosis transmembrane regulator protein) modulator therapy, particularly at a …
The evolving role of radiological imaging in cystic fibrosis
C Crowley, OJ O'Connor, P Ciet… - Current Opinion in …, 2021 - journals.lww.com
The recent introduction of triple-combination CF transmembrane regulator therapy has put
further emphasis on the need for sensitive methods of monitoring treatment response to …
further emphasis on the need for sensitive methods of monitoring treatment response to …
19F MRI of human lungs at 0.5 Tesla using octafluorocyclobutane
OS Pavlova, NV Anisimov, LL Gervits… - Magnetic …, 2020 - Wiley Online Library
Purpose The aim of this study was to demonstrate the feasibility of fluorine‐19 (19F) MRI of
the human lungs using octafluorocyclobutane (OFCB, C4F8). This gas has 8 magnetically …
the human lungs using octafluorocyclobutane (OFCB, C4F8). This gas has 8 magnetically …
[HTML][HTML] Imaging biomarkers of lung ventilation in interstitial lung disease from 129Xe and oxygen enhanced 1H MRI
Purpose To compare imaging biomarkers from hyperpolarised 129 Xe ventilation MRI and
dynamic oxygen-enhanced MRI (OE-MRI) with standard pulmonary function tests (PFT) in …
dynamic oxygen-enhanced MRI (OE-MRI) with standard pulmonary function tests (PFT) in …
1H‐guided reconstruction of 19F gas MRI in COPD patients
Purpose To reduce acquisition time and improve image quality and robustness of ventilation
assessment in a single breath‐hold using 1H‐guided reconstruction of fluorinated gas (19F) …
assessment in a single breath‐hold using 1H‐guided reconstruction of fluorinated gas (19F) …
Evaluation of fluorine‐19 magnetic resonance imaging of the lungs using octafluorocyclobutane in a rat model
Y Shepelytskyi, T Li, V Grynko… - Magnetic …, 2021 - Wiley Online Library
Purpose To test octafluorocyclobutane (OFCB) as an inhalation contrast agent for fluorine‐
19 MRI of the lung, and to compare the image quality of OFCB scans with perfluoropropane …
19 MRI of the lung, and to compare the image quality of OFCB scans with perfluoropropane …
An 8‐element Tx/Rx array utilizing MEMS detuning combined with 6 Rx loops for 19F and 1H lung imaging at 1.5T
Purpose To firstly improve the attainable image SNR of 19F and 1H C3F8 lung imaging at
1.5 tesla using an 8‐element transmit/receive (Tx/Rx) flexible vest array combined with a 6 …
1.5 tesla using an 8‐element transmit/receive (Tx/Rx) flexible vest array combined with a 6 …
MR properties of 19FC3F8 gas in the lungs of healthy volunteers: and apparent diffusion coefficient at 1.5T and at 3T
Purpose To measure the transverse relaxation time () and apparent diffusion coefficient
(ADC) of 19F‐C3F8 gas in vivo in human lungs at 1.5 T and 3T, and to determine the …
(ADC) of 19F‐C3F8 gas in vivo in human lungs at 1.5 T and 3T, and to determine the …
Dynamic susceptibility contrast 19F‐MRI of inhaled perfluoropropane: a novel approach to combined pulmonary ventilation and perfusion imaging
MA Neal, BJ Pippard, AJ Simpson… - Magnetic resonance in …, 2020 - Wiley Online Library
Purpose To assess alveolar perfusion by applying dynamic susceptibility contrast MRI to
19F‐MRI of inhaled perfluoropropane (PFP). We hypothesized that passage of gadolinium …
19F‐MRI of inhaled perfluoropropane (PFP). We hypothesized that passage of gadolinium …
Reproducibility of 19F‐MR ventilation imaging in healthy volunteers
BJ Pippard, MA Neal, AM Maunder… - Magnetic …, 2021 - Wiley Online Library
Purpose To assess the reproducibility of percentage ventilated lung volume (% VV)
measurements in healthy volunteers acquired by fluorine (19F)‐MRI of inhaled …
measurements in healthy volunteers acquired by fluorine (19F)‐MRI of inhaled …