[HTML][HTML] The aryl hydrocarbon receptor (AHR): A novel therapeutic target for pulmonary diseases?

B Shivanna, C Chu, B Moorthy - International Journal of Molecular …, 2022 - mdpi.com
The aryl hydrocarbon receptor (AHR) is a cytoplasmic transcription factor that is well-known
for regulating xenobiotic metabolism. Studies in knockout and transgenic mice indicate that …

[HTML][HTML] Current views in chronic obstructive pulmonary disease pathogenesis and management

AJ Alfahad, MM Alzaydi, AM Aldossary… - Saudi Pharmaceutical …, 2021 - Elsevier
Chronic obstructive pulmonary disease (COPD) is a progressive lung dysfunction caused
mainly by inhaling toxic particles and cigarette smoking (CS). The continuous exposure to …

[HTML][HTML] Pulmonary targeting of inhalable moxifloxacin microspheres for effective management of tuberculosis

B Vishwa, A Moin, DV Gowda, SMD Rizvi… - Pharmaceutics, 2021 - mdpi.com
In the present study, the objective was to attain a localized lung delivery of an anti-tubercular
fluoroquinolone, moxifloxacin (MXF), targeting the alveolar macrophages through a non …

Nanocarrier-based approaches to combat chronic obstructive pulmonary disease

T Virmani, G Kumar, R Virmani, A Sharma… - Nanomedicine, 2022 - Taylor & Francis
Abnormalities in airway mucus lead to chronic disorders in the pulmonary system such as
asthma, fibrosis and chronic obstructive pulmonary disease (COPD). Among these, COPD is …

Nanomedicines targeting respiratory injuries for pulmonary disease management

D Liu, M Long, L Gao, Y Chen, F Li… - Advanced Functional …, 2022 - Wiley Online Library
The respiratory system holds crucial importance in the biology of vertebrate animals. Injuries
of the respiratory system caused by viral infections (eg, by COVID‐19, MERS, and SARS) …

Design and fabrication of intracellular therapeutic cargo delivery systems based on nanomaterials: current status and future perspectives

H Ma, F Xing, Y Zhou, P Yu, R Luo, J Xu… - Journal of Materials …, 2023 - pubs.rsc.org
Intracellular cargo delivery, the introduction of small molecules, proteins, and nucleic acids
into a specific targeted site in a biological system, is an important strategy for deciphering …

Concepts of advanced therapeutic delivery systems for the management of remodeling and inflammation in airway diseases

DS Dhanjal, P Sharma, M Mehta… - Future Medicinal …, 2022 - Taylor & Francis
Chronic respiratory disorders affect millions of people worldwide. Pathophysiological
changes to the normal airway wall structure, including changes in the composition and …

Application of nanodrugs derived from active metabolites of medicinal plants for the treatment of inflammatory and lung diseases: recent advances

CO Adetunji, A Inobeme, OT Olaniyan, OO Ajayi… - Medicinal Plants for …, 2021 - Springer
Pulmonary diseases have been identified as one of the major diseases that are responsible
for higher level of mortality globally. The application of nanotechnology has been identified …

[HTML][HTML] Therapeutic potential of small molecules targeting oxidative stress in the treatment of chronic obstructive pulmonary disease (COPD): a comprehensive review

HG Dailah - Molecules, 2022 - mdpi.com
Chronic obstructive pulmonary disease (COPD) is an increasing and major global health
problem. COPD is also the third leading cause of death worldwide. Oxidative stress (OS) …

The contemplation of amylose for the delivery of ulcerogenic nonsteroidal anti-inflammatory drugs

R Fatima, P Prasher, M Sharma, SK Singh… - Future Medicinal …, 2024 - Taylor & Francis
This manuscript proposes an innovative approach to mitigate the gastrointestinal adversities
linked with nonsteroidal anti-inflammatory drugs (NSAIDs) by exploiting amylose as a novel …