[HTML][HTML] The aryl hydrocarbon receptor (AHR): A novel therapeutic target for pulmonary diseases?
B Shivanna, C Chu, B Moorthy - International Journal of Molecular …, 2022 - mdpi.com
The aryl hydrocarbon receptor (AHR) is a cytoplasmic transcription factor that is well-known
for regulating xenobiotic metabolism. Studies in knockout and transgenic mice indicate that …
for regulating xenobiotic metabolism. Studies in knockout and transgenic mice indicate that …
[HTML][HTML] Current views in chronic obstructive pulmonary disease pathogenesis and management
AJ Alfahad, MM Alzaydi, AM Aldossary… - Saudi Pharmaceutical …, 2021 - Elsevier
Chronic obstructive pulmonary disease (COPD) is a progressive lung dysfunction caused
mainly by inhaling toxic particles and cigarette smoking (CS). The continuous exposure to …
mainly by inhaling toxic particles and cigarette smoking (CS). The continuous exposure to …
[HTML][HTML] Pulmonary targeting of inhalable moxifloxacin microspheres for effective management of tuberculosis
In the present study, the objective was to attain a localized lung delivery of an anti-tubercular
fluoroquinolone, moxifloxacin (MXF), targeting the alveolar macrophages through a non …
fluoroquinolone, moxifloxacin (MXF), targeting the alveolar macrophages through a non …
Nanocarrier-based approaches to combat chronic obstructive pulmonary disease
Abnormalities in airway mucus lead to chronic disorders in the pulmonary system such as
asthma, fibrosis and chronic obstructive pulmonary disease (COPD). Among these, COPD is …
asthma, fibrosis and chronic obstructive pulmonary disease (COPD). Among these, COPD is …
Nanomedicines targeting respiratory injuries for pulmonary disease management
The respiratory system holds crucial importance in the biology of vertebrate animals. Injuries
of the respiratory system caused by viral infections (eg, by COVID‐19, MERS, and SARS) …
of the respiratory system caused by viral infections (eg, by COVID‐19, MERS, and SARS) …
Design and fabrication of intracellular therapeutic cargo delivery systems based on nanomaterials: current status and future perspectives
H Ma, F Xing, Y Zhou, P Yu, R Luo, J Xu… - Journal of Materials …, 2023 - pubs.rsc.org
Intracellular cargo delivery, the introduction of small molecules, proteins, and nucleic acids
into a specific targeted site in a biological system, is an important strategy for deciphering …
into a specific targeted site in a biological system, is an important strategy for deciphering …
Concepts of advanced therapeutic delivery systems for the management of remodeling and inflammation in airway diseases
Chronic respiratory disorders affect millions of people worldwide. Pathophysiological
changes to the normal airway wall structure, including changes in the composition and …
changes to the normal airway wall structure, including changes in the composition and …
Application of nanodrugs derived from active metabolites of medicinal plants for the treatment of inflammatory and lung diseases: recent advances
Pulmonary diseases have been identified as one of the major diseases that are responsible
for higher level of mortality globally. The application of nanotechnology has been identified …
for higher level of mortality globally. The application of nanotechnology has been identified …
[HTML][HTML] Therapeutic potential of small molecules targeting oxidative stress in the treatment of chronic obstructive pulmonary disease (COPD): a comprehensive review
HG Dailah - Molecules, 2022 - mdpi.com
Chronic obstructive pulmonary disease (COPD) is an increasing and major global health
problem. COPD is also the third leading cause of death worldwide. Oxidative stress (OS) …
problem. COPD is also the third leading cause of death worldwide. Oxidative stress (OS) …
The contemplation of amylose for the delivery of ulcerogenic nonsteroidal anti-inflammatory drugs
This manuscript proposes an innovative approach to mitigate the gastrointestinal adversities
linked with nonsteroidal anti-inflammatory drugs (NSAIDs) by exploiting amylose as a novel …
linked with nonsteroidal anti-inflammatory drugs (NSAIDs) by exploiting amylose as a novel …