The outcome of producing apoptotic defects in cancer cells is the primary obstacle that limits
the therapeutic efficacy of anticancer agents, and hence the development of novel agents …

Microtubules are dynamic polymers that occur in eukaryotic cells and play important roles in
cell division, motility, transport and signaling. They form during the process of polymerization …

Cancer remains a major health problem worldwide. Among many other factors, two
regulatory defects that are present in most cancer cells are constitutive activation of Janus …

Ionizing radiation results in extensive damage to biological systems. The massive amount of
ionizing radiation from nuclear accidents, radiation therapy (RT), space exploration, and the …

Signal transducer and activator of transcription protein 3 (STAT3) is a latent cytosolic
transcription factor that is widely recognized as being a master regulator of the cellular …

In this short review we report selected examples from recent literature to show the potential
of natural-derived, low molecular weight polyphenols as antitumor agents. The two major …

Melanoma is regarded as the fifth and sixth most common cancer in men and women,
respectively, and it is estimated that one person dies from melanoma every hour in the USA …

Considering the many secondary natural metabolites available from plants, phenolic
compounds play a particularly important role in human health as they occur in significant …

In the screening studies, cytotoxicity of 12 methylated resveratrol analogues on 11 human
cancer cell lines was examined. The most active compound 3, 4, 4′ 5-tetramethoxystilbene …

Chemoprevention is an approach to decrease cancer morbidity and mortality through
inhibition of carcinogenesis and prevention of disease progression. Although the trans …