Guideline-based management of asthma focuses on disease severity and choosing the
appropriate medical therapy to control symptoms and reduce the risk of exacerbations …

Background Asthma is a respiratory (airway) condition that affects an estimated 300 million
people worldwide and is associated with significant morbidity and mortality. Omalizumab is …

A new and potentially more pathogenic group of human rhinovirus (HRV), group C (HRVC),
has recently been discovered. We hypothesised that HRVC would be present in children …

The detection of low levels of pharmaceuticals in rivers and streams, drinking water, and
groundwater has raised questions as to whether these levels may affect human health. This …

Background: Current guidelines recommend the use of a combination of inhaled β2 agonists
and anticholinergics, particularly for patients with acute severe or life threatening asthma in …

Objectives: To provide physicians with current guidelines for the diagnosis and optimal
management of asthma in children and adults, including pregnant women and the elderly, in …

Background Systemic corticosteroid therapy is central to the management of acute asthma.
The use of inhaled corticosteroids (ICS) may also be beneficial in this setting. Objectives To …

Asthma is a prevalent chronic disease of the respiratory system and acute asthma
exacerbations are among the most common causes of presentation to the emergency …

Airway epithelial cells (AECs) provide the first line of defense in the respiratory tract and are
the main target of respiratory viruses. Here, using oligonucleotide and protein arrays, we …

Rationale: Human rhinovirus species C (HRV-C) is the most common cause of acute
wheezing exacerbations in young children presenting to hospital, but its impact on …